Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK11 | Q15759 | 6/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.49 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.44 |
| ▸ | OXTR | P30559 | 1/20 | 0.44 |
| ▸ | F2RL1 | P55085 | 4/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5983414 | 0.72 | CTSK (0.70) | — | |
| SCHEMBL8339904 | 0.71 | MAPK11 (0.45) | MAPK11MAPK14F2RL1CNR1CNR2 | |
| SCHEMBL8336645 | 0.70 | MAPK11 (0.47) | MAPK11MAPK14F2RL1MMP1MMP2 | |
| SCHEMBL3544059 | 0.70 | NPC1 (0.49) | HCRTR1HCRTR2 | |
| SCHEMBL8336585 | 0.69 | F2RL1 (0.66) | F2RL1CNR1CNR2 | |
| SCHEMBL6465448 | 0.68 | HCRTR1 (0.52) | HCRTR1HCRTR2 | |
| SCHEMBL8338299 | 0.68 | SMYD3 (0.47) | MAPK11MAPK14MMP1MMP2MMP3 | |
| SCHEMBL8490615 | 0.68 | HCRTR1 (0.44) | HCRTR1HCRTR2 | |
| SCHEMBL21162958 | 0.68 | F2RL1 (0.68) | F2RL1 | |
| SCHEMBL21162774 | 0.68 | F2RL1 (0.68) | F2RL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004017911-A2 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-03-04 | — | — | WO | disclosed |