Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1260061 | 0.79 | MEN1 (0.44) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL3720571 | 0.77 | GSK3B (0.46) | GSK3BHTR1AMAPTMEN1KMT2A | |
| SCHEMBL6788403 | 0.77 | GSK3B (0.70) | GSK3BHTR1AMAPTMEN1KMT2A | |
| SCHEMBL11600908 | 0.76 | GSK3B (0.44) | GSK3BHTR1AMAPTMEN1KMT2A | |
| SCHEMBL10681148 | 0.74 | HSP90AB1 (0.43) | ALDH1A1GAANPC1RAB9A | |
| SCHEMBL6202559 | 0.74 | GSK3B (0.41) | GSK3BHTR1AMAPTMEN1KMT2A | |
| SCHEMBL11848005 | 0.73 | ALDH1A1 (0.44) | GSK3BHTR1AMAPTMEN1KMT2A | |
| SCHEMBL2996683 | 0.73 | ALDH1A1 (0.44) | GSK3BHTR1AMAPTMEN1KMT2A | |
| SCHEMBL24264489 | 0.73 | LMNA (0.49) | HTR1AMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL287087 | 0.71 | ALDH1A1 (0.57) | GSK3BMAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050272036-A1 | Ketones | ASTRAZENECA AB (SE) | 2005-12-08 | — | — | US | disclosed |
| EP-1549600-A1 | KETONES | AstraZeneca AB (SE) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004011410-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-02-05 | — | — | WO | disclosed |