Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.38 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.38 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.38 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.38 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.38 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.38 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 3/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6204323 | 0.74 | GSK3B (0.43) | GSK3BALDH1A1KMT2ARAB9AHTR1A | |
| SCHEMBL6788403 | 0.73 | GSK3B (0.70) | GSK3BALDH1A1KMT2AHTTRAB9A | |
| SCHEMBL28366432 | 0.73 | HTR1A (0.45) | GSK3BKMT2AHTR1AKDRMAPT | |
| SCHEMBL4239545 | 0.71 | ALDH1A1 (0.50) | GSK3BALDH1A1KMT2AHTTRAB9A | |
| Methyl Alcohol SCHEMBL11791471 | 0.70 | HPGD (0.51) | GSK3BALDH1A1KMT2AHTTRAB9A | |
| SCHEMBL3720571 | 0.70 | GSK3B (0.46) | GSK3BALDH1A1KMT2AHTR1AMAPT | |
| SCHEMBL7472736 | 0.69 | ALDH1A1 (0.47) | GSK3BALDH1A1KMT2AHTTRAB9A | |
| SCHEMBL192389 | 0.69 | HPGD (0.54) | GSK3BALDH1A1KMT2AHTTRAB9A | |
| SCHEMBL24264489 | 0.69 | LMNA (0.49) | ALDH1A1KMT2AHTTRAB9AHTR1A | |
| SCHEMBL11600908 | 0.68 | GSK3B (0.44) | GSK3BALDH1A1KMT2ARAB9AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050272036-A1 | Ketones | ASTRAZENECA AB (SE) | 2005-12-08 | — | — | US | disclosed |
| EP-1549600-A1 | KETONES | AstraZeneca AB (SE) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004011410-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-02-05 | — | — | WO | disclosed |