Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | NQO2 | P16083 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.44 |
| ▸ | TUBB | P07437 | 1/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.44 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.44 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6205455 | 0.86 | KDM4E (0.48) | CHRM5RELACYP19A1CYP1A2TDP1 | |
| SCHEMBL6204838 | 0.80 | ALDH1A1 (0.47) | TDP1 | |
| SCHEMBL6204213 | 0.80 | RELA (0.45) | CHRM5RELANFE2L2CYP1A2FBP1 | |
| SCHEMBL16619043 | 0.78 | CHRM5 (0.60) | CHRM5RELANFE2L2CYP19A1NQO2 | |
| SCHEMBL6204379 | 0.76 | CHRM5 (0.53) | CHRM5RELANFE2L2CYP19A1NQO2 | |
| SCHEMBL28007509 | 0.75 | CHRM5 (0.56) | CHRM5RELANFE2L2CYP19A1NQO2 | |
| SCHEMBL27780191 | 0.75 | CHRM5 (0.56) | CHRM5RELANFE2L2CYP19A1NQO2 | |
| SCHEMBL1251512 | 0.75 | CHRM5 (0.56) | CHRM5RELANFE2L2CYP19A1NQO2 | |
| SCHEMBL6159256 | 0.74 | CHRM5 (0.55) | CHRM5RELANFE2L2CYP19A1NQO2 | |
| SCHEMBL27848978 | 0.74 | CHRM5 (0.55) | CHRM5RELANFE2L2CYP19A1NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506175-A1 | N-SUBSTITUTED TRICYCLIC 3-AMINOPYRAZOLES AS PDGF RECEPTOR INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-02-16 | — | — | EP | disclosed |
| WO-2003097609-A1 | N-SUBSTITUTED TRICYCLIC 3-AMINOPYRAZOLES AS PDFG RECEPTOR INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2003-11-27 | — | — | WO | disclosed |