Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | TSPO | P30536 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | CFTR | P13569 | 1/20 | 0.32 |
| ▸ | ATP4A | P20648 | 1/20 | 0.32 |
| ▸ | ATP4B | P51164 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6756623 | 0.88 | ALDH1A1 (0.42) | ALDH1A1HPGDTDP1FFAR1FFAR4 | |
| SCHEMBL29809738 | 0.83 | ALDH1A1 (0.56) | ALDH1A1HPGDTDP1FFAR1FFAR4 | |
| SCHEMBL1945874 | 0.83 | ALDH1A1 (0.56) | ALDH1A1HPGDTDP1FFAR1FFAR4 | |
| SCHEMBL9184322 | 0.83 | MEN1 (0.43) | ALDH1A1HPGDTDP1FFAR1FFAR4 | |
| SCHEMBL2422661 | 0.82 | ALDH1A1 (0.47) | ALDH1A1HPGDFFAR1FFAR4CYP1A1 | |
| SCHEMBL29534868 | 0.81 | TDP1 (0.55) | ALDH1A1TDP1FFAR1PTPN1APOBEC3G | |
| SCHEMBL31203 | 0.81 | TDP1 (0.55) | ALDH1A1TDP1FFAR1PTPN1APOBEC3G | |
| SCHEMBL27783461 | 0.78 | ALDH1A1 (0.44) | ALDH1A1HPGDTDP1FFAR1FFAR4 | |
| SCHEMBL7781555 | 0.78 | ALDH1A1 (0.44) | ALDH1A1HPGDFFAR1FFAR4CYP1A1 | |
| SCHEMBL11781897 | 0.77 | ATP4A (0.50) | ALDH1A1HPGDTDP1FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050192338-A1 | Process for the preparation of Ropinirole | CF PHARMA GYOGYSZERGYARTO KFT. (HU) | 2005-09-01 | — | — | US | disclosed |
| EP-1568689-A1 | Process for the preparation of the 2-oxoindole derivative, Ropinirole | Helm AG (DE) | 2005-08-31 | — | — | EP | disclosed |
| EP-1214282-B1 | HYDROFORMYLATION PROCESS UTILIZING MULTIDENTATE PHOSPHITE LIGANDS | INVISTA TECH SARL (US) | 2005-02-23 | — | — | EP | disclosed |
| US-6812352-B2 | REACTING AN ACYCLIC, ALIPHATIC, MONOETHYLENICALLY UNSATURATED COMPOUND WITH A SOURCE OF HCN IN THE PRESENCE OF A CATALYST PRECURSOR COMPOSITION COMPRISING A LEWIS ACID, A ZERO-VALENT NICKEL, AND A MULTIDENTATE PHOSPHITE LIGAND FOR HYDROCYANATION | INVISTA NORTH AMERICA S.A.R.L. | 2004-11-02 | — | — | US | disclosed |
| US-6515161-B1 | Multidentate phosphite ligands in a catalyst composition. In particular, the ligands have heteroatom-containing substituents on the carbon attached to the ortho position of the terminal phenol group. | E. I. DU PONT DE NEMOURS AND COMPANY | 2003-02-04 | — | — | US | disclosed |
| US-20030023110-A1 | Multidentate phosphite ligands, catalytic compositions containing such ligands, and catalytic prosses utilizing such catalytic compositions | INVISTA NORTH AMERICA S.A.R.L. | 2003-01-30 | — | — | US | disclosed |
| EP-1214282-A2 | HYDROFORMYLATION PROCESS UTILIZING MULTIDENTATE PHOSPHITE LIGANDS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2002-06-19 | — | — | EP | disclosed |
| EP-1214290-A1 | MULTIDENTATE PHOSPHITE LIGANDS AND CATALYTIC COMPOSITIONS CONTAINING THEM | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2002-06-19 | — | — | EP | disclosed |
| WO-2001021567-A2 | HYDROFORMYLATION PROCESS UTILIZING MULTIDENTATE PHOSPHITE LIGANDS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2001-03-29 | — | — | WO | disclosed |
| WO-2001021580-A1 | MULTIDENTATE PHOSPHITE LIGANDS, CATALYTIC COMPOSITIONS CONTAINING SUCH LIGANDS AND CATALYTIC PROCESSES UTILIZING SUCH CATALYTIC COMPOSITIONS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2001-03-29 | — | — | WO | disclosed |
| US-4826967-A | Psoralen-nucleoside adducts and method for their preparation | NAXCOR (US) | 1989-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050192338-A1 | Process for the preparation of Ropinirole | PRLHR, ADCYAP1R1, QDPR | ALDH1A1 1633/4885HPGD 1184/4885TDP1 1853/4885 |
| US-20030023110-A1 | Multidentate phosphite ligands, catalytic compositions containing such ligands, and catalytic prosses utilizing such catalytic compositions | PGM2, PAPSS1, PMM2 | ALDH1A1 4101/4885HPGD 727/4885TDP1 2576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.