Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 2/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.34 |
| ▸ | CCNE2 | O96020 | 7/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 7/20 | 0.33 |
| ▸ | CDK2 | P24941 | 7/20 | 0.33 |
| ▸ | PDE5A | O76074 | 3/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.32 |
| ▸ | PDE6C | P51160 | 2/20 | 0.32 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.32 |
| ▸ | WDR5 | P61964 | 1/20 | 0.31 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.31 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
| ▸ | STAT3 | P40763 | 1/20 | 0.30 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.30 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.30 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.30 |
| ▸ | CDK7 | P50613 | 1/20 | 0.30 |
| ▸ | CDK9 | P50750 | 1/20 | 0.30 |
| ▸ | CCNH | P51946 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6205006 | 0.87 | CDK1 (0.44) | CDK1CDK5CCNE2CCNE1CDK2 | |
| SCHEMBL6203737 | 0.86 | CDK1 (0.36) | CDK1CDK5CCNE2CCNE1CDK2 | |
| SCHEMBL3444723 | 0.80 | CDK1 (0.47) | CDK1CDK5CCNE2CCNE1CDK2 | |
| SCHEMBL3444325 | 0.79 | CDK2 (0.50) | CDK1CDK5CCNE2CCNE1CDK2 | |
| SCHEMBL3443903 | 0.78 | CDK2 (0.42) | CDK1CDK5CCNE1CDK2JAK3 | |
| SCHEMBL6204543 | 0.78 | CCNE1 (0.37) | CDK1CDK5CCNE2CCNE1CDK2 | |
| SCHEMBL3444183 | 0.78 | BCDIN3D (0.39) | CDK1CCNE2CCNE1CDK2STAT3 | |
| SCHEMBL6204991 | 0.77 | PKM (0.42) | CCNE2CCNE1CDK2CCNT1CDK9 | |
| SCHEMBL6205631 | 0.76 | CCNE2 (0.44) | CDK1CDK5CCNE2CCNE1CDK2 | |
| SCHEMBL6204092 | 0.75 | CCNT1 (0.31) | CDK5CCNE1CDK2CCNT1CDK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539760-A2 | AZAPURINE DERIVATIVES | INSTITUTE OF EXPERIMENTAL BOTANY ASCR (CZ) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004018473-A2 | AZAPURINE DERIVATIVES | INSTITUTE OF EXPERIMENTAL BOTANY ASCR (CZ) | 2004-03-04 | — | — | WO | disclosed |