Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE2 | O96020 | 5/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.44 |
| ▸ | CDK2 | P24941 | 5/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 3/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | KCNH3 | Q9ULD8 | 3/20 | 0.31 |
| ▸ | CFTR | P13569 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6206198 | 0.90 | CCNE2 (0.46) | CCNE2CCNE1CDK2HTR2CCDK1 | |
| SCHEMBL6203776 | 0.89 | CDK5 (0.46) | CCNE2CCNE1CDK2CDK5ATM | |
| SCHEMBL6205006 | 0.86 | CDK1 (0.44) | CCNE2CCNE1CDK2CDK5CDK5R1 | |
| SCHEMBL6203210 | 0.83 | CCNE2 (0.42) | CCNE2CCNE1CDK2CDK5ATM | |
| SCHEMBL6204543 | 0.81 | CCNE1 (0.37) | CCNE2CCNE1CDK2CDK5CDK5R1 | |
| SCHEMBL6203902 | 0.76 | CCNE2 (0.31) | CCNE2CCNE1CDK2 | |
| SCHEMBL6205415 | 0.76 | CDK1 (0.34) | CCNE2CCNE1CDK2CDK5CDK5R1 | |
| SCHEMBL6204991 | 0.76 | PKM (0.42) | CCNE2CCNE1CDK2 | |
| SCHEMBL3445689 | 0.75 | CDK5 (0.46) | CCNE2CCNE1CDK2CDK5CDK5R1 | |
| SCHEMBL3445478 | 0.74 | KCNH3 (0.53) | CCNE2CCNE1CDK2CDK5CDK5R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539760-A2 | AZAPURINE DERIVATIVES | INSTITUTE OF EXPERIMENTAL BOTANY ASCR (CZ) | 2005-06-15 | — | — | EP | claimed |
| WO-2004018473-A2 | AZAPURINE DERIVATIVES | INSTITUTE OF EXPERIMENTAL BOTANY ASCR (CZ) | 2004-03-04 | — | — | WO | claimed |