Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | CTSG | P08311 | 1/20 | 0.50 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.50 |
| ▸ | CMA1 | P23946 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | ELANE | P08246 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6205636 | 0.92 | NR4A2 (0.65) | NR4A2L3MBTL1MAPTLMNATDP1 | |
| SCHEMBL4826769 | 0.87 | NR4A2 (0.55) | NR4A2L3MBTL1MAPTLMNATDP1 | |
| SCHEMBL2437915 | 0.81 | L3MBTL1 (0.59) | NR4A2L3MBTL1MAPTLMNATDP1 | |
| SCHEMBL135356 | 0.81 | NR4A2 (0.61) | NR4A2L3MBTL1MAPTLMNATDP1 | |
| Benzoic Acid SCHEMBL27660361 | 0.80 | TSHR (0.61) | NR4A2L3MBTL1MAPTLMNAALDH1A1 | |
| Benzoic Acid SCHEMBL20985707 | 0.80 | ALDH1A1 (0.54) | L3MBTL1LMNAALDH1A1KMT2AHPGD | |
| SCHEMBL28689137 | 0.80 | L3MBTL1 (0.50) | NR4A2L3MBTL1MAPTLMNATDP1 | |
| SCHEMBL719034 | 0.79 | NR4A2 (0.85) | NR4A2L3MBTL1MAPTLMNATDP1 | |
| SCHEMBL30121738 | 0.79 | NR4A2 (0.85) | NR4A2L3MBTL1MAPTLMNATDP1 | |
| SCHEMBL8729152 | 0.79 | KMT2A (0.49) | NR4A2L3MBTL1MAPTLMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1317466-B1 | SYNTHONS FOR OLIGONUCLEOTIDE SYNTHESIS | AVECIA BIOTECHNOLOGY INC (US) | 2005-02-23 | — | — | EP | disclosed |
| US-20030229218-A1 | Synthons for oligonucleotide synthesis | AVECIA BIOTECHNOLOGY INC. | 2003-12-11 | — | — | US | disclosed |
| EP-1317466-A2 | SYNTHONS FOR OLIGONUCLEOTIDE SYNTHESIS | Avecia Biotechnology, Inc. (US) | 2003-06-11 | — | — | EP | disclosed |
| WO-2002020543-A2 | SYNTHONS FOR OLIGONUCLEOTIDE SYNTHESIS | AVECIA BIOTECHNOLOGY INC. (US) | 2002-03-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030229218-A1 | Synthons for oligonucleotide synthesis | POLI, TYMP, POLRMT | NR4A2 4402/4885L3MBTL1 2317/4885MAPT 3167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.