Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CUL4A | Q13619 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | XDH | P47989 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6207825 | 0.79 | HSD17B10 (0.33) | HSD17B10KDM4EHPGDCUL4AMAPT | |
| SCHEMBL3465913 | 0.74 | HSD17B10 (0.50) | HSD17B10KDM4EHPGDCUL4AMAPT | |
| SCHEMBL3672729 | 0.69 | KDM4E (0.37) | HSD17B10KDM4EHPGDMAPTTSHR | |
| SCHEMBL10804734 | 0.64 | HPGD (0.41) | HSD17B10KDM4EHPGDMAPTKMT2A | |
| SCHEMBL4971363 | 0.62 | — | — | |
| SCHEMBL20796 | 0.62 | — | — | |
| SCHEMBL4748477 | 0.62 | ALDH1A1 (0.54) | HSD17B10KDM4EHPGDTSHRGAA | |
| SCHEMBL676909 | 0.62 | KMT2A (0.58) | HSD17B10KDM4EHPGDMAPTKMT2A | |
| SCHEMBL9237989 | 0.62 | KMT2A (0.42) | HSD17B10KDM4EHPGDMAPTTSHR | |
| SCHEMBL1401584 | 0.60 | RECQL (0.39) | HSD17B10KDM4EHPGDMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1298133-B1 | Procedure for the alkylation of 3,4-dihydroxythiophene-2,5-dicarboxylic esters | BAYER CHEMICALS AG (DE) | 2005-01-19 | — | — | EP | claimed |
| EP-1298133-A1 | Procedure for the alkylation of 3,4-dihydroxythiophene-2,5-dicarboxylic esters | BAYER AG (DE) | 2003-04-02 | — | — | EP | claimed |
| EP-1298133-B1 | Procedure for the alkylation of 3,4-dihydroxythiophene-2,5-dicarboxylic esters | BAYER CHEMICALS AG (DE) | 2005-01-19 | — | — | EP | disclosed |
| EP-1298133-A1 | Procedure for the alkylation of 3,4-dihydroxythiophene-2,5-dicarboxylic esters | BAYER AG (DE) | 2003-04-02 | — | — | EP | disclosed |
| EP-0628560-A1 | Thiophene derivatives | Agfa-Gevaert AG (DE) | 1994-12-14 | — | — | EP | disclosed |