Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.63 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.55 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | BCR | P11274 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL722198 | 0.84 | PDPK1 (0.77) | PDPK1LOXL2ADRB2CYP2A6SMPD3 | |
| 2-Phenylthiazole SCHEMBL70646 | 0.77 | PDPK1 (1.00) | PDPK1LOXL2ADRB2CYP2A6SMPD3 | |
| SCHEMBL1653986 | 0.77 | PDPK1 (0.68) | PDPK1LOXL2ADRB2CYP2A6SMPD3 | |
| SCHEMBL744756 | 0.76 | CYP2A6 (0.53) | PDPK1LOXL2ADRB2CYP2A6SMPD3 | |
| SCHEMBL533513 | 0.76 | PDPK1 (0.60) | PDPK1LOXL2ADRB2CYP2A6SMPD3 | |
| 2-Phenylthiazole SCHEMBL10667585 | 0.76 | PDPK1 (0.95) | PDPK1LOXL2ADRB2CYP2A6SMPD3 | |
| SCHEMBL17704291 | 0.76 | PDPK1 (0.65) | PDPK1LOXL2ADRB2CYP2A6SMPD3 | |
| 2-Phenylthiazole SCHEMBL10519953 | 0.76 | PDPK1 (0.95) | PDPK1LOXL2ADRB2CYP2A6SMPD3 | |
| 2-Phenylthiazole SCHEMBL4939218 | 0.76 | PDPK1 (0.95) | PDPK1LOXL2ADRB2CYP2A6SMPD3 | |
| 2-Phenylthiazole SCHEMBL28319382 | 0.76 | PDPK1 (0.95) | PDPK1LOXL2ADRB2CYP2A6SMPD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 652 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210353631-A1 | 1,4-Benzoxazines for the Treatment of Cancers and Other Neurodegenerative Diseases | Neugeneron LLC | 2021-11-18 | — | — | US | claimed |
| US-20200274077-A1 | PHOTOELECTRIC CONVERSION ELEMENT AND IMAGING APPARATUS | SONY CORPORATION (JP) | 2020-08-27 | — | — | US | claimed |
| CN-111316459-A | Photoelectric conversion element and imaging device | 索尼公司 | 2020-06-19 | — | — | CN | claimed |
| CN-106349184-A | Preparation method of 2- (ortho-alkylaryl) benzothiazole series | 江西师范大学 | 2017-01-25 | — | — | CN | claimed |
| EP-2415763-B1 | PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING GLAUCOMA | UBE INDUSTRIES (JP) | 2016-01-27 | — | — | EP | claimed |
| US-20150299163-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF PARASITIC DISEASES | IRBM - SCIENCE PARK S.P.A. (IT) | 2015-10-22 | — | — | US | claimed |
| CN-102448940-B | For the medical composition of glaucomatous treatment or prevention | UBE INDUSTRIES, LTD. (JP) | 2015-10-21 | — | — | CN | claimed |
| EP-2914589-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF PARASITIC DISEASES | IRBM - Science Park S.p.A. (IT) | 2015-09-09 | — | — | EP | claimed |
| CN-103124774-B | Metal complex dye, photo-electric conversion element and photoelectrochemical cell | FUJIFILM CORP. (JP) | 2015-08-19 | — | — | CN | claimed |
| CN-101970410-B | Pyridylaminoacetic acid compounds | UBE INDUSTRIES | 2014-06-25 | — | — | CN | claimed |
| WO-1997040029-A1 | ANTIVIRALLY ACTIVE HETEROCYCLIC AZAHEXANE DERIVATIVES | NOVARTIS AG (CH) | 1997-10-30 | — | — | WO | claimed |
| WO-1997024343-A1 | PHENYL THIAZOLE DERIVATIVES WITH ANTI HERPES VIRUS PROPERTIES | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1997-07-10 | — | — | WO | claimed |
| EP-0772594-A1 | IMINOXYCARBOXYLATES AND DERIVATIVES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | Abbott Laboratories (US) | 1997-05-14 | — | — | EP | claimed |
| WO-1996033170-A1 | N-AROYLAMINO ACID AMIDES AS ENDOTHELIN INHIBITORS | NOVARITS AG (CH) | 1996-10-24 | — | — | WO | claimed |
| EP-0728145-A1 | ENDOTHELIN RECEPTOR ANTAGONISTS | Ciba-Geigy Japan Limited (JP) | 1996-08-28 | — | — | EP | claimed |
| WO-1996002507-A1 | IMINOXYCARBOXYLATES AND DERIVATIVES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | ABBOTT LABORATORIES (US) | 1996-02-01 | — | — | WO | claimed |
| EP-0674635-A1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS | ZENECA LIMITED (GB) | 1995-10-04 | — | — | EP | claimed |
| WO-1995012611-A1 | ENDOTHELIN RECEPTOR ANTAGONISTS | JAPAT LTD. (CH) | 1995-05-11 | — | — | WO | claimed |
| WO-1994014803-A1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS | ZENECA LIMITED (GB) | 1994-07-07 | — | — | WO | claimed |
| CN-1065070-A | 11 beta-aryl-4-estrenes of 6,7-sex change | SCHERING AG (DE) | 1992-10-07 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150299163-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF PARASITIC DISEASES | HDAC3, HDAC5, HDAC1 | PDPK1 1486/4885LOXL2 3565/4885ADRB2 4474/4885 |
| US-20210353631-A1 | 1,4-Benzoxazines for the Treatment of Cancers and Other Neurodegenerative Diseases | GBA1, NFXL1, CYP4X1 | PDPK1 1423/4885LOXL2 2527/4885ADRB2 2997/4885 |
| US-20200274077-A1 | PHOTOELECTRIC CONVERSION ELEMENT AND IMAGING APPARATUS | PPOX, JUP, L1CAM | PDPK1 620/4885LOXL2 1597/4885ADRB2 4660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.