Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6204652 | 0.85 | TTR (0.50) | ALDH1A1LMNAGAAHTTSMN1; SMN2 | |
| SCHEMBL5913357 | 0.85 | HTT (0.42) | ALDH1A1LMNAGAAHTTSMN1; SMN2 | |
| SCHEMBL5913083 | 0.81 | SMN1; SMN2 (0.48) | ALDH1A1LMNAGAAHTTSMN1; SMN2 | |
| SCHEMBL29839233 | 0.80 | ALDH1A1 (0.53) | ALDH1A1MAPTPTPN1 | |
| SCHEMBL1130254 | 0.80 | ALDH1A1 (0.53) | ALDH1A1MAPTPTPN1 | |
| SCHEMBL4977602 | 0.80 | ALDH1A1 (0.60) | ALDH1A1LMNAGAAHTTSMN1; SMN2 | |
| SCHEMBL5913800 | 0.79 | TTR (0.45) | ALDH1A1LMNAGAAHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11873461 | 0.78 | ALDH1A1 (0.63) | ALDH1A1LMNAGAAHTTSMN1; SMN2 | |
| SCHEMBL30062398 | 0.78 | HSPB1 (0.56) | ALDH1A1LMNAGAAHTTSMN1; SMN2 | |
| SCHEMBL397137 | 0.78 | HSPB1 (0.56) | ALDH1A1LMNAGAAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1738798-A | Indole derivatives as somatostatin agonists or antagonists | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2006-02-22 | — | — | CN | disclosed |
| EP-1562898-A1 | INDOLE DERIVATIVES AS SOMATOSTATIN AGONISTS OR ANTAGONISTS | Takeda Pharmaceutical Company Limited (JP) | 2005-08-17 | — | — | EP | disclosed |
| WO-2004046107-A1 | INDOLE DERIVATIVES AS SOMATOSTATIN AGONISTS OR ANTAGONISTS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-06-03 | — | — | WO | disclosed |