Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 14/20 | 0.58 |
| ▸ | ITGA1 | P56199 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.47 |
| ▸ | WDR5 | P61964 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6206113 | 1.00 | ACLY (0.58) | ACLYITGA1HDAC1USP2ALPL | |
| SCHEMBL6206114 | 1.00 | ACLY (0.58) | ACLYITGA1HDAC1USP2ALPL | |
| SCHEMBL6207007 | 0.87 | ITGA1 (0.69) | ITGA1HDAC1USP2WDR5 | |
| SCHEMBL6204782 | 0.87 | ITGA1 (0.69) | ITGA1HDAC1USP2WDR5 | |
| SCHEMBL6207012 | 0.87 | ITGA1 (0.69) | ITGA1HDAC1USP2WDR5 | |
| SCHEMBL6204447 | 0.87 | ITGA1 (0.57) | ITGA1USP2WDR5 | |
| SCHEMBL6204438 | 0.87 | ITGA1 (0.57) | ITGA1USP2WDR5 | |
| SCHEMBL6204444 | 0.87 | ITGA1 (0.57) | ITGA1USP2WDR5 | |
| SCHEMBL6204122 | 0.86 | ITGA1 (0.50) | ACLYITGA1USP2WDR5 | |
| SCHEMBL6204118 | 0.86 | ITGA1 (0.50) | ACLYITGA1USP2WDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100763-B1 | DIKETOACID-DERIVATIVES AS INHIBITORS OF POLYMERASES | ANGELETTI P IST RICHERCHE BIO (IT) | 2005-06-22 | — | — | EP | claimed |