Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA1 | P56199 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | WDR5 | P61964 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SLC25A1 | P53007 | 1/20 | 0.47 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6204447 | 1.00 | ITGA1 (0.57) | ITGA1MAPK1USP2MEN1KMT2A | |
| SCHEMBL6204444 | 1.00 | ITGA1 (0.57) | ITGA1MAPK1USP2MEN1KMT2A | |
| SCHEMBL6207012 | 0.91 | ITGA1 (0.69) | ITGA1MAPK1USP2MEN1KMT2A | |
| SCHEMBL6207007 | 0.91 | ITGA1 (0.69) | ITGA1MAPK1USP2MEN1KMT2A | |
| SCHEMBL6204782 | 0.91 | ITGA1 (0.69) | ITGA1MAPK1USP2MEN1KMT2A | |
| SCHEMBL6205383 | 0.88 | ITGA1 (0.53) | ITGA1USP2MEN1KMT2AWDR5 | |
| SCHEMBL6205102 | 0.88 | ITGA1 (0.53) | ITGA1USP2MEN1KMT2AWDR5 | |
| SCHEMBL6205381 | 0.88 | ITGA1 (0.53) | ITGA1USP2MEN1KMT2AWDR5 | |
| SCHEMBL6206115 | 0.87 | ACLY (0.58) | ITGA1USP2WDR5 | |
| SCHEMBL6206114 | 0.87 | ACLY (0.58) | ITGA1USP2WDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100763-B1 | DIKETOACID-DERIVATIVES AS INHIBITORS OF POLYMERASES | ANGELETTI P IST RICHERCHE BIO (IT) | 2005-06-22 | — | — | EP | claimed |