Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 1/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6203895 | 0.91 | POLB (0.49) | HPGDALDH1A1POLBMEN1KMT2A | |
| SCHEMBL6206617 | 0.90 | POLB (0.50) | HPGDALDH1A1POLBMEN1KMT2A | |
| SCHEMBL6208399 | 0.85 | RAB9A (0.58) | HPGDALDH1A1RAB9AHRH3TSHR | |
| SCHEMBL6204183 | 0.84 | POLB (0.72) | HPGDALDH1A1POLBMEN1KMT2A | |
| SCHEMBL6206415 | 0.80 | KDM4E (0.60) | HPGDALDH1A1POLBHSD17B10KDM4E | |
| SCHEMBL6205208 | 0.79 | CHRM3 (0.53) | HPGDALDH1A1POLBMEN1KMT2A | |
| SCHEMBL6205610 | 0.78 | HPGD (0.47) | HPGDALDH1A1POLBMEN1KMT2A | |
| SCHEMBL6206035 | 0.77 | MAPT (0.58) | HPGDALDH1A1POLBKMT2ANPC1 | |
| SCHEMBL6206009 | 0.77 | HPGD (0.58) | HPGDALDH1A1POLBNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL6205334 | 0.76 | MAPT (0.57) | HPGDALDH1A1POLBKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1177177-B1 | SUBSTITUTED 4-OXO-QUINOLINE-3-CARBOXAMIDES: GABA BRAIN RECEPTOR LIGANDS | NEUROGEN CORP (US) | 2005-02-23 | — | — | EP | claimed |