Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | POLA1 | P09884 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6205245 | 0.93 | HPGD (0.55) | HPGDALDH1A1KCNH2POLBMAPT | |
| SCHEMBL6204849 | 0.85 | HRH3 (0.60) | HPGDALDH1A1POLBMAPTF2 | |
| SCHEMBL6205208 | 0.84 | CHRM3 (0.53) | HPGDALDH1A1POLBTSHRHRH3 | |
| Hydrochloric Acid SCHEMBL6205556 | 0.84 | HRH3 (0.59) | HPGDALDH1A1KCNH2POLBMAPT | |
| SCHEMBL6205758 | 0.83 | HPGD (0.58) | HPGDALDH1A1KCNH2POLBMAPT | |
| SCHEMBL6207917 | 0.82 | RAB9A (0.56) | HPGDALDH1A1POLBMAPTUSP2 | |
| SCHEMBL6205197 | 0.82 | POLB (0.61) | HPGDALDH1A1KCNH2POLBMAPT | |
| SCHEMBL6206374 | 0.81 | ADORA2A (0.58) | HPGDALDH1A1POLBMAPTHSD17B10 | |
| SCHEMBL6206360 | 0.79 | ADORA2A (0.51) | HPGDALDH1A1POLBHSD17B10NPC1 | |
| SCHEMBL6208399 | 0.79 | RAB9A (0.58) | HPGDALDH1A1TSHRHRH3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1177177-B1 | SUBSTITUTED 4-OXO-QUINOLINE-3-CARBOXAMIDES: GABA BRAIN RECEPTOR LIGANDS | NEUROGEN CORP (US) | 2005-02-23 | — | — | EP | claimed |