Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
| ▸ | GUSB | P08236 | 10/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6206418 | 0.85 | HPGD (0.60) | RAB9AHRH3HPGDALDH1A1TSHR | |
| SCHEMBL6203895 | 0.84 | POLB (0.49) | RAB9AHRH3HPGDALDH1A1TSHR | |
| SCHEMBL6206617 | 0.83 | POLB (0.50) | RAB9AHRH3HPGDALDH1A1TSHR | |
| SCHEMBL6207917 | 0.83 | RAB9A (0.56) | RAB9AGUSBHPGDALDH1A1 | |
| SCHEMBL6230868 | 0.83 | RAB9A (0.80) | RAB9AGUSB | |
| Hydrochloric Acid SCHEMBL6204618 | 0.82 | RAB9A (0.79) | RAB9AGUSB | |
| SCHEMBL6206035 | 0.81 | MAPT (0.58) | RAB9AHRH3HPGDALDH1A1 | |
| SCHEMBL6205208 | 0.81 | CHRM3 (0.53) | RAB9AHRH3HPGDALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL6205334 | 0.80 | MAPT (0.57) | RAB9AHRH3HPGDALDH1A1 | |
| SCHEMBL6204754 | 0.80 | MAPT (0.59) | RAB9AHRH3HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1177177-B1 | SUBSTITUTED 4-OXO-QUINOLINE-3-CARBOXAMIDES: GABA BRAIN RECEPTOR LIGANDS | NEUROGEN CORP (US) | 2005-02-23 | — | — | EP | claimed |