Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4464439 | 0.83 | TSHR (0.50) | TSHRLMNAALDH1A1MEN1MAPT | |
| SCHEMBL27847422 | 0.81 | TSHR (0.50) | CNR1ACHETSHRLMNASMN1; SMN2 | |
| SCHEMBL6025006 | 0.80 | ALDH1A1 (0.63) | CNR1TSHRLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL3408351 | 0.79 | PKM (0.54) | CNR1TSHRLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL3345913 | 0.79 | PKM (0.61) | CNR1TSHRLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL11177460 | 0.79 | PKM (0.58) | CNR1TSHRLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL1150747 | 0.78 | CNR1 (0.53) | CNR1ACHETSHRLMNASMN1; SMN2 | |
| SCHEMBL4578854 | 0.77 | CNR1 (0.66) | CNR1TSHRSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL13286855 | 0.75 | SMN1; SMN2 (0.57) | TSHRLMNASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL16345591 | 0.75 | LMNA (0.54) | CNR1TSHRLMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1532132-A1 | NOVEL BENZODIOXOLES | F.HOFFMANN-LA ROCHE AG (CH) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004013120-A1 | NOVEL BENZODIOXOLES | F. HOFFMANN-LA ROCHE AG (CH) | 2004-02-12 | — | — | WO | disclosed |