SCHEMBL6206583

SCHEMBL6206583

c1ccc(-c2cccc(-c3ccccc3)c2)cc1.c1ccc(Cc2ccc(-c3ccccc3)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.57
TAAR1 Q96RJ0 4/20 0.56
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
CA9 Q16790 1/20 0.52
CA14 Q9ULX7 1/20 0.52
CYP17A1 P05093 3/20 0.52
CYP3A4 P08684 3/20 0.52
CYP11B1 P15538 3/20 0.52
CYP11B2 P19099 3/20 0.52
CYP19A1 P11511 2/20 0.52
PTPN5 P54829 3/20 0.51
ACMSD Q8TDX5 1/20 0.51
AGXT P21549 2/20 0.50
IDH1 O75874 1/20 0.48
MEN1 O00255 1/20 0.46
ESR1 P03372 1/20 0.46
KMT2A Q03164 1/20 0.46
ABCC4 O15439 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29040199 0.91 ACMSD (0.61) CALM1TAAR1CA12CA1CA2
SCHEMBL27326 0.90 CALM1 (0.71) CALM1TAAR1CA12CA1CA2
SCHEMBL9625135 0.88 CALM1 (0.60) CALM1TAAR1CYP11B1CYP11B2CYP19A1
SCHEMBL31498880 0.88 CALM1 (0.60) CALM1TAAR1CYP11B1CYP11B2CYP19A1
SCHEMBL31498881 0.88 CALM1 (0.60) CALM1TAAR1CYP11B1CYP11B2CYP19A1
Methane SCHEMBL9562367 0.87 CALM1 (0.67) CALM1TAAR1CA12CA1CA2
Tannin Pyrogallol SCHEMBL29187616 0.87 CALM1 (0.75) CALM1TAAR1CA12CA1CA2
SCHEMBL269952 0.87 CALM1 (0.65) CALM1TAAR1CA12CA1CA2
SCHEMBL198432 0.87 CALM1 (0.75) CALM1TAAR1CA12CA1CA2
SCHEMBL2843937 0.85 AGXT (0.59) CALM1TAAR1CYP11B1CYP11B2CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030139293-A1 Heat sensitive recording material CIBA SPECIALTY CHEMICALS CORP. 2003-07-24 US claimed
EP-0928794-B1 Crystalline flouran compounds and their use in recording materials CIBA SC HOLDING AG (CH) 2005-03-09 EP disclosed
US-6635602-B1 Heat sensitive and pressure sensitive recording material; synthesised directly by the reaction of two derivatives of amino phenols, phthalic anhydrides, keto acids and/or diphenylamines with a phenol derivative CIBA SPECIALTY CHEMICALS CORPORATION 2003-10-21 US disclosed
US-6566302-B1 For use in heat sensitive and pressure sensitive recording materials CIBA SPECIALTY CHEMICALS CORPORATION 2003-05-20 US disclosed
EP-1107972-B1 PREPARATION PROCESS FOR MANUFACTURE AND PURIFICATION OF MIXTURES OF FLUORAN COMPOUNDS AND RECORDING MATERIAL COMPRISING SAID MIXTURES OF FLUORAN CIBA SC HOLDING AG (CH) 2003-01-02 EP disclosed
EP-1115579-A1 MONOPHASE SOLID SOLUTIONS COMPRISING A PLURALITY OF COLOUR FORMER COMPOUNDS AND PROCESS FOR THEIR PREPARATION Ciba SC Holding AG (CH) 2001-07-18 EP disclosed
EP-1107972-A1 PREPARATION PROCESS FOR MANUFACTURE AND PURIFICATION OF MIXTURES OF FLUORAN COMPOUNDS AND RECORDING MATERIAL COMPRISING SAID MIXTURES OF FLUORAN Ciba SC Holding AG (CH) 2001-06-20 EP disclosed
US-6071853-A Crystalline fluoran compound CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-06-06 US disclosed
WO-2000012318-A1 MONOPHASE SOLID SOLUTIONS COMPRISING A PLURALITY OF COLOUR FORMER COMPOUNDS AND PROCESS FOR THEIR PREPARATION CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-03-09 WO disclosed
WO-2000012513-A1 NOVEL PREPARATION PROCESS FOR MANUFACTURE AND PURIFICATION OF MIXTURES OF FLUORAN COMPOUNDS AND RECORDING MATERIAL COMPRISING SAID MIXTURES OF FLUORAN COMPOUNDS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-03-09 WO disclosed
EP-0928794-A1 Crystalline flouran compounds and their use in recording materials Ciba SC Holding AG (CH) 1999-07-14 EP disclosed