SCHEMBL269952

SCHEMBL269952

c1ccc(-c2ccc(Cc3ccc(-c4ccccc4)cc3)cc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.65
TAAR1 Q96RJ0 3/20 0.62
ALDH1A1 P00352 2/20 0.56
CA12 O43570 1/20 0.56
CA1 P00915 1/20 0.56
CA2 P00918 1/20 0.56
CA9 Q16790 1/20 0.56
CA14 Q9ULX7 1/20 0.56
IDO1 P14902 2/20 0.54
AGXT P21549 2/20 0.54
ABCC4 O15439 1/20 0.54
LMNA P02545 1/20 0.54
GAA P10253 1/20 0.54
TSHR P16473 1/20 0.54
PTGS1 P23219 1/20 0.54
HTT P42858 1/20 0.54
FFAR1 O14842 1/20 0.50
LTA4H P09960 2/20 0.48
CYP3A4 P08684 2/20 0.48
MAPK1 P28482 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27326 0.97 CALM1 (0.71) CALM1TAAR1ALDH1A1CA12CA1
Methane SCHEMBL9562367 0.94 CALM1 (0.67) CALM1TAAR1ALDH1A1CA12CA1
SCHEMBL198432 0.94 CALM1 (0.75) CALM1TAAR1ALDH1A1CA12CA1
Tannin Pyrogallol SCHEMBL29187616 0.94 CALM1 (0.75) CALM1TAAR1ALDH1A1CA12CA1
Diphenylmethane SCHEMBL10336493 0.90 CALM1 (0.80) CALM1TAAR1ALDH1A1CA12CA1
SCHEMBL7940599 0.87 CYP11B1 (0.52) CALM1TAAR1CA12CA1CA2
SCHEMBL9798989 0.87 CYP3A4 (0.71) CALM1TAAR1ALDH1A1CA12CA1
SCHEMBL7938048 0.87 MMP3 (0.71) CALM1TAAR1IDO1AGXTABCC4
SCHEMBL8752792 0.87 MEN1 (0.51) CALM1TAAR1ALDH1A1CA12CA1
SCHEMBL8752833 0.87 CYP1A2 (0.71) CALM1TAAR1CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 426 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1053742-B1 Anhydrous skin care or make-up compositions containing fibres and polyols OREAL (FR) 2004-08-04 EP claimed
EP-1064930-B1 Care or make-up composition containing fibers and a hydrophilic organopolysiloxane OREAL (FR) 2002-02-06 EP claimed
EP-0891767-B1 Glossy composition containing aromatic oils thickened with an alkylether of a polysaccharide OREAL (FR) 2001-07-18 EP claimed
EP-1064930-A1 Care or make-up composition containing fibers and a hydrophilic organopolysiloxane L'OREAL (FR) 2001-01-03 EP claimed
EP-1053742-A1 Anhydrous skin care or make-up compositions containing fibres and polyols L'OREAL (FR) 2000-11-22 EP claimed
US-5961998-A Glossy composition containing aromatic oils thickened by a polysaccharide ether L'OREAL (FR) 1999-10-05 US claimed
US-11944698-B2 Dispersion with a dispersed fatty phase having a high pigment content CAPSUM (FR) 2024-04-02 US disclosed
WO-2024056706-A1 METHOD FOR FORMING A DISPERSION COMPRISING DROPS AND ASSOCIATED DEVICE CAPSUM (FR) 2024-03-21 WO disclosed
US-11931445-B2 Composition comprising baicalin L'OREAL (FR) 2024-03-19 US disclosed
US-20240041712-A1 COMPOSITION IN THE FORM OF A STABLE MACROSCOPIC EMULSION COMPRISING A PERCENTAGE OF INGREDIENTS OF NATURAL ORIGIN THAT IS GREATER THAN OR EQUAL TO 95% ACCORDING TO ISO STANDARD 16128 CAPSUM (FR) 2024-02-08 US disclosed
US-20240024209-A1 HYDRATING COMPOSITION COMPRISING POLYMERS AND A COMPOUND CHOSEN FROM MENTHOL AND ITS DERIVATIVES L'OREAL (FR) 2024-01-25 US disclosed
WO-2024003116-A1 SOLID COSMETIC HAIR CARE COMPOSITION HAVING AT LEAST ONE CAVITY CAPSUM (FR) 2024-01-04 WO disclosed
EP-4288020-A1 COMPOSITION IN THE FORM OF A STABLE MACROSCOPIC EMULSION COMPRISING A PERCENTAGE OF INGREDIENTS OF NATURAL ORIGIN THAT IS GREATER THAN OR EQUAL TO 95% ACCORDING TO ISO STANDARD 16128 Capsum (FR) 2023-12-13 EP disclosed
WO-2002055051-A1 COMPOSITIONS, IN PARTICULAR COSMETIC, WITH OPTICAL PROPERTY L'OREAL (FR) 2002-07-18 WO disclosed
WO-2002055040-A1 CLEANSING COMPOSITION CONTAINING AN AMPHIPHILIC POLYMER L'OREAL (FR) 2002-07-18 WO disclosed
EP-1213008-A2 Make-up or bodycare composition containing fibres and a dispersing copolymer L'OREAL (FR) 2002-06-12 EP disclosed
EP-1064930-B1 Care or make-up composition containing fibers and a hydrophilic organopolysiloxane OREAL (FR) 2002-02-06 EP disclosed
EP-1064930-A1 Care or make-up composition containing fibers and a hydrophilic organopolysiloxane L'OREAL (FR) 2001-01-03 EP disclosed
EP-1053742-A1 Anhydrous skin care or make-up compositions containing fibres and polyols L'OREAL (FR) 2000-11-22 EP disclosed
EP-1008339-A1 Cosmetic composition containing an association of acexamic acid and polyols L'OREAL (FR) 2000-06-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11944698-B2 Dispersion with a dispersed fatty phase having a high pigment content PLIN3, PLIN1, PLIN5 CALM1 4419/4885TAAR1 4164/4885ALDH1A1 424/4885
US-20240024209-A1 HYDRATING COMPOSITION COMPRISING POLYMERS AND A COMPOUND CHOSEN FROM MENTHOL AND ITS DERIVATIVES ALG1, MGLL, MLEC CALM1 1670/4885TAAR1 2124/4885ALDH1A1 3184/4885
US-20240041712-A1 COMPOSITION IN THE FORM OF A STABLE MACROSCOPIC EMULSION COMPRISING A PERCENTAGE OF INGREDIENTS OF NATURAL ORIGIN THAT IS GREATER THAN OR EQUAL TO 95% ACCORDING TO ISO STANDARD 16128 RPL28, RPS28, ERG28 CALM1 3232/4885TAAR1 2920/4885ALDH1A1 1142/4885
US-11931445-B2 Composition comprising baicalin KRT18, S100A6, DSG1 CALM1 3526/4885TAAR1 3927/4885ALDH1A1 2732/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.