Methane

Methane

SCHEMBL9562367

C.c1ccc(Cc2ccc(-c3ccccc3)cc2)cc1

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.67
CA12 O43570 1/20 0.57
CA1 P00915 1/20 0.57
CA2 P00918 1/20 0.57
CA9 Q16790 1/20 0.57
CA14 Q9ULX7 1/20 0.57
TAAR1 Q96RJ0 2/20 0.56
LTA4H P09960 2/20 0.52
LMNA P02545 3/20 0.50
ALDH1A1 P00352 3/20 0.50
IDO1 P14902 2/20 0.50
AGXT P21549 2/20 0.50
ABCC4 O15439 1/20 0.50
GAA P10253 1/20 0.50
TSHR P16473 1/20 0.50
PTGS1 P23219 1/20 0.50
HTT P42858 1/20 0.50
IDH1 O75874 1/20 0.48
FFAR1 O14842 1/20 0.46
PLA2G10 O15496 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27326 0.97 CALM1 (0.71) CALM1CA12CA1CA2CA9
SCHEMBL198432 0.94 CALM1 (0.75) CALM1CA12CA1CA2CA9
SCHEMBL269952 0.94 CALM1 (0.65) CALM1CA12CA1CA2CA9
Tannin Pyrogallol SCHEMBL29187616 0.94 CALM1 (0.75) CALM1CA12CA1CA2CA9
Diphenylmethane SCHEMBL10336493 0.91 CALM1 (0.80) CALM1CA12CA1CA2CA9
SCHEMBL6206583 0.87 CALM1 (0.57) CALM1CA12CA1CA2CA9
SCHEMBL7039574 0.85 MMP3 (0.68) CALM1CA12CA1CA2CA9
SCHEMBL972712 0.85 CALM1 (0.92) CALM1CA12CA1CA2CA9
Diphenylmethane SCHEMBL1867544 0.85 CALM1 (0.92) CALM1LTA4HLMNAALDH1A1IDO1
SCHEMBL8094422 0.85 CALM1 (0.92) CALM1CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5200385-A Comprising leuco dye, color developer and water soluble alkylphosphate lubricants; antifogging, smoothness RICOH COMPANY, LTD. (JP) 1993-04-06 US disclosed
US-5126486-A Color developers for leuco dyes in thermal printing RICOH COMPANY, LTD. (JP) 1992-06-30 US disclosed
US-4978651-A With a colorless or light colored leuco dye for inducing color formation RICOH COMPANY, LTD. (JP) 1990-12-18 US disclosed