Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KDM3B | Q7LBC6 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | PRKAB2 | O43741 | 3/20 | 0.35 |
| ▸ | PRKAG1 | P54619 | 3/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.35 |
| ▸ | PRKAA1 | Q13131 | 3/20 | 0.35 |
| ▸ | PRKAG3 | Q9UGI9 | 3/20 | 0.35 |
| ▸ | PRKAG2 | Q9UGJ0 | 3/20 | 0.35 |
| ▸ | PRKAB1 | Q9Y478 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6208699 | 0.80 | KDM4E (0.43) | KDM4EALDH1A1HPGDKDM3BDYRK1A | |
| SCHEMBL6208722 | 0.78 | KDM4E (0.44) | KDM4EHPGDKDM3BDYRK1AHSD17B10 | |
| SCHEMBL6207236 | 0.77 | DYRK1A (0.47) | KDM4EALDH1A1HPGDKDM3BDYRK1A | |
| SCHEMBL6208284 | 0.76 | KDM4E (0.40) | KDM4EALDH1A1HPGDKDM3BDYRK1A | |
| SCHEMBL6207480 | 0.75 | KDM4E (0.44) | KDM4EALDH1A1HPGDKDM3BDYRK1A | |
| SCHEMBL6207870 | 0.74 | KDM4E (0.41) | KDM4EHPGDKDM3BDYRK1AHSD17B10 | |
| Hydrochloric Acid SCHEMBL6437034 | 0.73 | TDP1 (0.47) | KDM4EALDH1A1HSD17B10MAPTTDP1 | |
| SCHEMBL8119170 | 0.72 | ALDH1A1 (0.44) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL7121722 | 0.72 | PRNP (0.38) | KDM4EALDH1A1KDM3BDYRK1ACSNK2A2 | |
| SCHEMBL3245100 | 0.70 | TDP1 (0.49) | ALDH1A1HSD17B10MAPTTDP1CSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546133-A2 | N-SUBSTITUTE-2-OXODIHYDROPYRIDINE DERIVATIVES AS NPY ANTAGONISTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004031175-A2 | N-SUBSTITUTED-2-OXODIHYDROPYRIDINE DERIVATIVES AS NPY ANTAGONISTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-04-15 | — | — | WO | disclosed |