Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | KDM3B | Q7LBC6 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6207480 | 0.86 | KDM4E (0.44) | KDM4EKDM3BDYRK1ACSNK2A1CSNK2A2 | |
| SCHEMBL6208699 | 0.81 | KDM4E (0.43) | KDM4EKDM3BDYRK1ACSNK2A1CSNK2A2 | |
| SCHEMBL6207236 | 0.81 | DYRK1A (0.47) | KDM4EKDM3BDYRK1ACSNK2A1CSNK2A2 | |
| SCHEMBL6206909 | 0.78 | KDM4E (0.41) | KDM4EKDM3BDYRK1ACSNK2A1CSNK2A2 | |
| SCHEMBL7121722 | 0.76 | PRNP (0.38) | KDM4EKDM3BDYRK1ACSNK2A1CSNK2A2 | |
| SCHEMBL6207870 | 0.75 | KDM4E (0.41) | KDM4EKDM3BDYRK1ACSNK2A1CSNK2A2 | |
| SCHEMBL27695803 | 0.72 | HCAR2 (0.43) | KDM4EKDM3BCSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL10901788 | 0.71 | GABRP (0.43) | KDM4ECSNK2A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL6208037 | 0.70 | DYRK1A (0.52) | KDM4EKDM3BDYRK1ACSNK2A1CSNK2A2 | |
| SCHEMBL27412755 | 0.69 | KDM4E (0.42) | KDM4ECSNK2A1NOTUMGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546133-A2 | N-SUBSTITUTE-2-OXODIHYDROPYRIDINE DERIVATIVES AS NPY ANTAGONISTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004031175-A2 | N-SUBSTITUTED-2-OXODIHYDROPYRIDINE DERIVATIVES AS NPY ANTAGONISTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-04-15 | — | — | WO | disclosed |