Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | CPT2 | P23786 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | ACACA | Q13085 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5849651 | 0.79 | FAAH (0.51) | MAPTFAAHFFAR1 | |
| SCHEMBL6910766 | 0.78 | CA2 (0.47) | MAPTFAAHFFAR1TDP1CA2 | |
| SCHEMBL5855960 | 0.77 | MAPT (0.34) | MAPTFAAHCA2 | |
| SCHEMBL6848288 | 0.77 | MAPT (0.34) | MAPTFAAHCA2 | |
| SCHEMBL1702873 | 0.76 | FAAH (0.42) | MAPTFAAHFFAR1 | |
| SCHEMBL1703441 | 0.76 | FAAH (0.42) | MAPTFAAHFFAR1 | |
| SCHEMBL6080210 | 0.76 | FAAH (0.39) | MAPTFAAHFFAR1TDP1 | |
| SCHEMBL4089567 | 0.76 | FAAH (0.42) | MAPTFAAHFFAR1 | |
| SCHEMBL186371 | 0.75 | FFAR1 (0.33) | FFAR1CPT2TDP1 | |
| SCHEMBL2224240 | 0.75 | MAPT (0.37) | MAPTFAAHTDP1CA2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1564200-A1 | Ketone compounds and compositions for cholesterol management and related uses | Esperion Therapeutics Inc. (US) | 2005-08-17 | — | — | EP | disclosed |
| WO-2002030860-A9 | KETONE COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | ESPERION THERAPEUTICS INC (US) | 2003-02-20 | — | — | WO | disclosed |