Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.33 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2224240 | 0.93 | MAPT (0.37) | FAAHMAPTTDP1MEN1KMT2A | |
| SCHEMBL5849651 | 0.87 | FAAH (0.51) | FAAHMAPTACE2GPR84FFAR1 | |
| SCHEMBL1703441 | 0.84 | FAAH (0.42) | FAAHMAPTACE2GPR84FFAR1 | |
| SCHEMBL1702873 | 0.84 | FAAH (0.42) | FAAHMAPTACE2GPR84FFAR1 | |
| SCHEMBL4089567 | 0.84 | FAAH (0.42) | FAAHMAPTACE2GPR84FFAR1 | |
| SCHEMBL6910766 | 0.83 | CA2 (0.47) | FAAHMAPTACE2GPR84FFAR1 | |
| SCHEMBL1890789 | 0.80 | TDP1 (0.49) | MAPTGPR84FFAR1LCKPPARD | |
| SCHEMBL14685886 | 0.79 | ALDH1A1 (0.43) | FAAHMAPTALDH1A1TDP1MEN1 | |
| SCHEMBL335124 | 0.79 | CHRM1 (0.41) | FAAHMAPTACE2GPR84FFAR1 | |
| SCHEMBL11069012 | 0.79 | TP53 (0.44) | FAAHMAPTACE2GPR84FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7038072-B2 | Process for monoalkylation of C-H acidic methylene groups | DEGUSSA AG (DE) | 2006-05-02 | — | — | US | disclosed |
| US-20040054226-A1 | Process for monoalkylation of C-H acidic methylene groups | DEGUSSA AG | 2004-03-18 | — | — | US | disclosed |