Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5855960 | 0.85 | MAPT (0.34) | MAPTFAAHCA1CA2 | |
| SCHEMBL2224240 | 0.81 | MAPT (0.37) | MAPTFAAHCA1CA2 | |
| SCHEMBL6910766 | 0.80 | CA2 (0.47) | MAPTFAAHCA1CA2 | |
| SCHEMBL6080210 | 0.78 | FAAH (0.39) | MAPTFAAH | |
| SCHEMBL1771998 | 0.78 | MAPT (0.36) | MAPTFAAH | |
| SCHEMBL5849651 | 0.78 | FAAH (0.51) | MAPTFAAH | |
| SCHEMBL335124 | 0.77 | CHRM1 (0.41) | MAPTFAAHCA1CA2 | |
| SCHEMBL6207356 | 0.77 | MAPT (0.33) | MAPTFAAHCA2 | |
| SCHEMBL6851285 | 0.75 | MAPT (0.32) | MAPT | |
| SCHEMBL4089567 | 0.75 | FAAH (0.42) | MAPTFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661289-B1 | Vinyl carboxamide derivatives as insecticides and acaricides | SYNGENTA PARTICIPATIONS AG (CH) | 2004-03-03 | — | — | EP | disclosed |
| US-5763481-A | PESTICIDES; INSECTICIDES, MITICIDES | NOVARTIS CORPROATION (US) | 1998-06-09 | — | — | US | disclosed |
| US-5545630-A | PESTICIDES | CIBA-GEIGY CORPORATION (US) | 1996-08-13 | — | — | US | disclosed |
| EP-0661289-A1 | Vinyl carboxamide derivatives as insecticides and acaricides | CIBA-GEIGY AG (CH) | 1995-07-05 | — | — | EP | disclosed |