Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | GUSB | P08236 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6205758 | 0.90 | HPGD (0.58) | RAB9AHPGDADORA2AALDH1A1SMN1; SMN2 | |
| SCHEMBL6205245 | 0.89 | HPGD (0.55) | RAB9AHPGDADORA2AALDH1A1CHRM3 | |
| SCHEMBL6205238 | 0.86 | NPC1 (0.55) | RAB9AHPGDALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL6207397 | 0.85 | MAPT (0.53) | RAB9AHPGDALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL6205185 | 0.85 | HPGD (0.56) | RAB9AHPGDADORA2AALDH1A1CHRM3 | |
| SCHEMBL6206287 | 0.85 | HPGD (0.60) | RAB9AHPGDADORA2AALDH1A1CHRM3 | |
| Hydrochloric Acid SCHEMBL6206718 | 0.85 | NPC1 (0.54) | RAB9AHPGDALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL6208399 | 0.83 | RAB9A (0.58) | RAB9AHPGDALDH1A1GUSB | |
| SCHEMBL6206009 | 0.82 | HPGD (0.58) | RAB9AHPGDALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL6205565 | 0.82 | POLB (0.62) | RAB9AHPGDALDH1A1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1177177-B1 | SUBSTITUTED 4-OXO-QUINOLINE-3-CARBOXAMIDES: GABA BRAIN RECEPTOR LIGANDS | NEUROGEN CORP (US) | 2005-02-23 | — | — | EP | claimed |