SCHEMBL620863

SCHEMBL620863

CN(C)C1(P(C2CCCCC2)C2CCCCC2)CC=CC=C1c1ccccc1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
SLC6A3 Q01959 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6386581 0.99
SCHEMBL382831 0.81
SCHEMBL27224621 0.80
SCHEMBL27766224 0.78
SCHEMBL6543142 0.78 NR5A2 (0.30)
SCHEMBL28662481 0.78 SLC6A2 (0.31) SLC6A2SLC6A4SLC6A3
SCHEMBL14150161 0.75
SCHEMBL22750238 0.74 OPRK1 (0.30)
SCHEMBL30523299 0.69 KDM4E (0.33)
SCHEMBL28344710 0.66 OPRL1 (0.37) SLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240327355-A1 METHOD FOR PRODUCING ARYLAMIDE DERIVATIVE CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-10-03 US claimed
EP-4375273-A1 METHOD FOR PRODUCING ARYLAMIDE DERIVATIVE CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-05-29 EP claimed
CN-117677607-A Process for producing aryl amide derivative 中外制药株式会社 2024-03-08 CN claimed
WO-2023003014-A1 METHOD FOR PRODUCING ARYLAMIDE DERIVATIVE 中外製薬株式会社 2023-01-26 WO claimed
EP-4741400-A1 MULTIMERIC MANGANESE CONTRAST AGENTS Bayer Aktiengesellschaft (DE) 2026-05-13 EP disclosed
US-12590089-B2 Processes for preparing toll-like receptor modulator compounds GILEAD SCIENCES, INC. (US) 2026-03-31 US disclosed
US-20260027113-A1 PHTHALAZINONE BASED MODULATORS FOR THE TREATMENT OF DISEASE SOLEY THERAPEUTICS INC (US) 2026-01-29 US disclosed
EP-4676547-A2 ALPHA-SYNUCLEIN BINDERS AND METHODS OF USE Merck Sharp & Dohme LLC (US) 2026-01-14 EP disclosed
EP-4676922-A1 BIFUNCTIONAL COMPOUNDS CAPABLE OF DEGRADING ANDROGEN RECEPTORS Astrazeneca AB (SE) 2026-01-14 EP disclosed
US-12465603-B2 Phthalazinone based modulators for the treatment of disease SOLEY THERAPEUTICS, INC. (US) 2025-11-11 US disclosed
EP-4619387-A1 PHTHALAZINONE BASED MODULATORS FOR THE TREATMENT OF DISEASE Soley Therapeutics, Inc. (US) 2025-09-24 EP disclosed
US-12410196-B2 Benzopyrimidine compounds and use thereof USYNOVA PHARMACEUTICALS LTD. (CN) 2025-09-09 US disclosed
WO-2003101601-A2 CROSS-COUPLING SYNTHESIS OF ALKYL (DIALKYLPHENYL) INDENES BOULDER SCIENTIFIC COMPANY (US) 2003-12-11 WO disclosed
WO-2003076398-A2 PYRROLE-2, 5-DIONE DERIVATIVES AND THEIR USE AS GSK-3 INHIBITORS ELI LILLY AND COMPANY (US) 2003-09-18 WO disclosed
EP-1276726-A2 SUBSTITUTED PHENYL FARNESYLTRANSFERASE INHIBITORS Abbott Laboratories (US) 2003-01-22 EP disclosed
EP-1254124-A1 DIPEPTIDE NITRILE CATHPSIN K INHIBITORS Novartis AG (CH) 2002-11-06 EP disclosed
WO-2002079207-A2 TRI-AND BIDENTATE AMIDO LIGANDS PREPARED BY PALLADIUM0 COUPLING AND METALLATION THEREOF TO FORM METAL-AMIDO CATALYSTS CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2002-10-10 WO disclosed
CN-1336912-A Novel propargylether derivatives SINGTENTA PARTICIPATION AG (CH) 2002-02-20 CN disclosed
WO-2001081316-A2 SUBSTITUTED PHENYL FARNESYLTRANSFERASE INHIBITORS ABBOTT LABORATORIES (US) 2001-11-01 WO disclosed
WO-2001058886-A1 DIPEPTIDE NITRILE CATHEPSIN K INHIBITORS NOVARTIS AG (CH) 2001-08-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12590089-B2 Processes for preparing toll-like receptor modulator compounds TLR8, MYD88, TLR6 SLC6A2 4105/4885SLC6A4 4114/4885SLC6A3 3092/4885
US-12465603-B2 Phthalazinone based modulators for the treatment of disease MKI67, BCL2, CCAR2 SLC6A2 4369/4885SLC6A4 4640/4885SLC6A3 4517/4885
US-20260027113-A1 PHTHALAZINONE BASED MODULATORS FOR THE TREATMENT OF DISEASE NCOR1, NOP56, NCOR2 SLC6A2 3843/4885SLC6A4 4306/4885SLC6A3 3853/4885
US-12410196-B2 Benzopyrimidine compounds and use thereof DPYD, CYP2D6, TYMP SLC6A2 1730/4885SLC6A4 1727/4885SLC6A3 2452/4885
US-20240327355-A1 METHOD FOR PRODUCING ARYLAMIDE DERIVATIVE BRAF, RAF1, NRAS SLC6A2 3823/4885SLC6A4 3999/4885SLC6A3 2645/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.