Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 7/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22129387 | 0.75 | PNMT (0.31) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28349143 | 0.75 | SLC6A2 (0.30) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3992253 | 0.74 | ALDH1A1 (0.31) | — | |
| SCHEMBL28634495 | 0.73 | OPRM1 (0.32) | OPRL1OPRM1OPRK1TAAR1 | |
| SCHEMBL27519463 | 0.72 | SLC6A3 (0.38) | OPRL1OPRM1OPRK1TAAR1SLC6A2 | |
| SCHEMBL1153470 | 0.71 | MAOA (0.33) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27709376 | 0.71 | CYP19A1 (0.30) | — | |
| SCHEMBL27892872 | 0.71 | — | — | |
| Biphenyl SCHEMBL28511221 | 0.71 | ALDH1A1 (0.33) | OPRL1OPRM1OPRK1TAAR1SLC6A2 | |
| SCHEMBL27511534 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107074851-B | As αvβ6Naphthyridine derivatives of integrin antagonists for the treatment of e.g. fibrotic diseases | 葛兰素史密斯克莱知识产权发展有限公司 | 2020-01-10 | — | — | CN | disclosed |