Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 17/20 | 0.68 |
| ▸ | CTSL | P07711 | 17/20 | 0.68 |
| ▸ | CTSB | P07858 | 16/20 | 0.68 |
| ▸ | CTSK | P43235 | 16/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4700960 | 1.00 | CTSS (0.68) | CTSSCTSLCTSBCTSK | |
| SCHEMBL4698804 | 0.91 | CTSL (0.66) | CTSSCTSLCTSBCTSK | |
| SCHEMBL6210052 | 0.90 | CTSK (0.57) | CTSSCTSLCTSBCTSK | |
| SCHEMBL6209952 | 0.87 | CTSS (0.71) | CTSSCTSLCTSBCTSK | |
| SCHEMBL4698932 | 0.87 | CTSS (0.71) | CTSSCTSLCTSBCTSK | |
| SCHEMBL4699860 | 0.85 | CTSK (0.72) | CTSSCTSLCTSBCTSK | |
| SCHEMBL4699494 | 0.85 | CTSL (0.71) | CTSSCTSLCTSBCTSK | |
| SCHEMBL4701344 | 0.84 | CTSL (0.75) | CTSSCTSLCTSBCTSK | |
| SCHEMBL6209073 | 0.84 | CTSL (0.56) | CTSSCTSLCTSBCTSK | |
| SCHEMBL4700947 | 0.83 | CTSL (0.66) | CTSSCTSLCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1372655-A4 | CATHEPSIN CYSTEINE PROTEASE INHIBITORS | MERCK FROSST CANADA INC (CA) | 2005-10-12 | — | — | EP | claimed |
| EP-1372655-A2 | CATHEPSIN CYSTEINE PROTEASE INHIBITORS | Merck Frosst Canada & Co. (CA) | 2004-01-02 | — | — | EP | claimed |
| WO-2002069901-A2 | CATHEPSIN CYSTEINE PROTEASE INHIBITORS | MERCK FROSST CANADA & CO. (CA) | 2002-09-12 | — | — | WO | claimed |