Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 9/20 | 0.42 |
| ▸ | CTSS | P25774 | 9/20 | 0.42 |
| ▸ | CTSV | O60911 | 2/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 10/20 | 0.39 |
| ▸ | PREP | P48147 | 5/20 | 0.35 |
| ▸ | FAP | Q12884 | 5/20 | 0.35 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.35 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4049892 | 0.89 | CTSS (0.37) | CTSLCTSSCTSVUSP30CTSK | |
| SCHEMBL4041994 | 0.81 | CTSS (0.39) | CTSLCTSSCTSVUSP30CTSK | |
| SCHEMBL8348192 | 0.81 | CTSK (0.53) | CTSLCTSSCTSVCTSKPREP | |
| SCHEMBL4040427 | 0.80 | CTSK (0.54) | CTSLCTSSCTSVUSP30CTSK | |
| SCHEMBL4038477 | 0.80 | CTSS (0.40) | CTSLCTSSCTSVUSP30CTSK | |
| SCHEMBL4043711 | 0.79 | CTSS (0.43) | CTSLCTSSCTSVUSP30CTSK | |
| SCHEMBL4039394 | 0.79 | CTSL (0.42) | CTSLCTSSCTSVCTSKCTSB | |
| SCHEMBL4050085 | 0.79 | CTSS (0.40) | CTSLCTSSCTSVUSP30CTSK | |
| SCHEMBL6210005 | 0.78 | CTSS (0.42) | CTSLCTSSCTSVCTSKPREP | |
| SCHEMBL4048072 | 0.78 | CTSV (0.39) | CTSLCTSSCTSVCTSKHTRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | claimed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | claimed |
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | disclosed |