Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | PLD2 | O14939 | 1/20 | 0.37 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6210232 | 0.90 | KMT2A (0.52) | NAMPTKMT2AMEN1HDAC6CTSK | |
| SCHEMBL6210300 | 0.88 | DPP4 (0.47) | NAMPTKMT2AMEN1HDAC6CTSK | |
| SCHEMBL6212982 | 0.88 | CTSK (0.50) | NAMPTKMT2AMEN1HDAC6CTSK | |
| SCHEMBL6209530 | 0.88 | CHRM4 (0.43) | NAMPTKMT2AMEN1HDAC6CTSK | |
| SCHEMBL6211258 | 0.88 | KMT2A (0.54) | NAMPTKMT2AMEN1CTSKDPP4 | |
| SCHEMBL6210886 | 0.87 | DPP4 (0.37) | NAMPTKMT2AMEN1HDAC6DPP4 | |
| SCHEMBL6210377 | 0.86 | CTSK (0.40) | NAMPTKMT2AMEN1CTSKDRD3 | |
| SCHEMBL6210116 | 0.85 | TLR7 (0.44) | NAMPTKMT2AMEN1CTSKDPP4 | |
| SCHEMBL6211589 | 0.85 | RAB9A (0.46) | NAMPTKMT2AMEN1HDAC6CTSK | |
| SCHEMBL6211548 | 0.85 | CHRM4 (0.42) | NAMPTKMT2AMEN1HDAC6CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | claimed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | claimed |