Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | PREP | P48147 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 4/20 | 0.38 |
| ▸ | DRD4 | P21917 | 4/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.36 |
| ▸ | TACR3 | P29371 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6211916 | 0.87 | CHRM4 (0.40) | CHRM4DPP4PREPDRD2DRD4 | |
| SCHEMBL6210300 | 0.87 | DPP4 (0.47) | DPP4NAMPTHDAC3HDAC1MEN1 | |
| SCHEMBL6210232 | 0.87 | KMT2A (0.52) | DPP4NAMPTHDAC3HDAC1MEN1 | |
| SCHEMBL6212982 | 0.86 | CTSK (0.50) | DRD2NAMPTHDAC3HDAC1MEN1 | |
| SCHEMBL6211258 | 0.85 | KMT2A (0.54) | DPP4DRD2HTR2ANAMPTHDAC3 | |
| SCHEMBL6209350 | 0.85 | NAMPT (0.40) | DPP4DRD2DRD4HTR2ANAMPT | |
| SCHEMBL6209530 | 0.85 | CHRM4 (0.43) | CHRM4DPP4NAMPTMEN1KMT2A | |
| SCHEMBL6212663 | 0.84 | TAOK1 (0.39) | DPP4NAMPTHDAC3HDAC1MEN1 | |
| SCHEMBL6211589 | 0.83 | RAB9A (0.46) | CHRM4DPP4NAMPTHDAC3HDAC1 | |
| SCHEMBL6210116 | 0.83 | TLR7 (0.44) | DPP4PREPNAMPTHDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | claimed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | claimed |