Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | DPP4 | P27487 | 3/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6211258 | 0.92 | KMT2A (0.54) | KMT2ADPP4NAMPTCTSKMEN1 | |
| SCHEMBL6210116 | 0.90 | TLR7 (0.44) | KMT2ADPP4NAMPTCTSKMEN1 | |
| SCHEMBL6211589 | 0.90 | RAB9A (0.46) | CHRM4KMT2ADPP4NAMPTHDAC6 | |
| SCHEMBL6210232 | 0.90 | KMT2A (0.52) | KMT2ADPP4NAMPTHDAC6CTSK | |
| SCHEMBL6212982 | 0.88 | CTSK (0.50) | KMT2ANAMPTHDAC6CTSKMEN1 | |
| SCHEMBL6210300 | 0.88 | DPP4 (0.47) | KMT2ADPP4NAMPTHDAC6CTSK | |
| SCHEMBL6209350 | 0.88 | NAMPT (0.40) | KMT2ADPP4NAMPTHDAC6CTSK | |
| SCHEMBL6211548 | 0.85 | CHRM4 (0.42) | CHRM4KMT2ADPP4NAMPTHDAC6 | |
| SCHEMBL6211807 | 0.85 | DPP4 (0.42) | CHRM4KMT2ADPP4MAPK14NAMPT | |
| SCHEMBL6212663 | 0.84 | TAOK1 (0.39) | KMT2ADPP4NAMPTHDAC6CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | disclosed |