Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | PTAFR | P25105 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 2/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6213867 | 0.93 | CHRM4 (0.40) | CXCR3LMNAPOLBHPGDCHRM4 | |
| SCHEMBL6212257 | 0.93 | POLB (0.40) | CXCR3GAALMNAKMT2APOLB | |
| SCHEMBL6275935 | 0.92 | NAMPT (0.41) | CXCR3LMNAPOLBHPGDCHRM4 | |
| SCHEMBL6208718 | 0.91 | LMNA (0.42) | GAALMNAKMT2AHPGDCHRM4 | |
| SCHEMBL6211570 | 0.90 | SLC6A5 (0.38) | LMNACHRM4CCR5NAMPTSMYD3 | |
| SCHEMBL6211038 | 0.90 | CTSK (0.41) | GAACHRNB2CHRNA7CHRNA4LMNA | |
| SCHEMBL6212884 | 0.90 | LMNA (0.37) | LMNAHPGDCHRM4SMYD3 | |
| SCHEMBL6209651 | 0.90 | LMNA (0.42) | CXCR3GAALMNAKMT2APOLB | |
| SCHEMBL6209295 | 0.89 | CTSK (0.37) | LMNAKMT2ASMYD3 | |
| SCHEMBL6211651 | 0.89 | NAMPT (0.38) | LMNATP53NAMPTSMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | claimed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | claimed |