Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6211570 | 0.94 | SLC6A5 (0.38) | LMNASMYD3NAMPTCHRM4 | |
| SCHEMBL6209450 | 0.91 | CXCR3 (0.43) | LMNAKMT2ASMYD3GAAHPGD | |
| SCHEMBL6211038 | 0.91 | CTSK (0.41) | LMNAALDH1A1HTTCTSKMEN1 | |
| SCHEMBL6212884 | 0.90 | LMNA (0.37) | LMNAALDH1A1HTTSMYD3HPGD | |
| SCHEMBL6275935 | 0.90 | NAMPT (0.41) | LMNAHTTSMYD3HPGDSMN1; SMN2 | |
| SCHEMBL6209295 | 0.90 | CTSK (0.37) | LMNAALDH1A1CTSKMEN1KMT2A | |
| SCHEMBL6213867 | 0.90 | CHRM4 (0.40) | LMNASMYD3HPGDCHRM4 | |
| SCHEMBL6211651 | 0.89 | NAMPT (0.38) | LMNAALDH1A1MAPTSMYD3SMN1; SMN2 | |
| SCHEMBL6212257 | 0.89 | POLB (0.40) | LMNARAB9AKMT2ASMYD3GAA | |
| SCHEMBL6210230 | 0.88 | ROCK2 (0.40) | LMNAALDH1A1SMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | claimed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | claimed |
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | disclosed |