Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.65 |
| ▸ | FABP4 | P15090 | 1/20 | 0.65 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.65 |
| ▸ | CDK2 | P24941 | 1/20 | 0.65 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.65 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.63 |
| ▸ | SNCA | P37840 | 2/20 | 0.44 |
| ▸ | CHAT | P28329 | 1/20 | 0.44 |
| ▸ | CD40 | P25942 | 3/20 | 0.42 |
| ▸ | CD40LG | P29965 | 3/20 | 0.42 |
| ▸ | FABP1 | P07148 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6214963 | 0.82 | TTR (0.68) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL12355064 | 0.81 | TTR (0.49) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL43158 | 0.79 | FABP4 (1.00) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL29381891 | 0.79 | FABP4 (1.00) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL6210682 | 0.79 | TTR (0.72) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL11057825 | 0.79 | TTR (0.63) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL6210121 | 0.78 | MAPK14 (0.66) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL6654772 | 0.78 | FABP4 (0.97) | TTRFABP4CCNA2CDK2MAPK14 | |
| Ammonia Solution, Strong SCHEMBL592280 | 0.78 | NR4A1 (1.00) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL10353163 | 0.78 | FABP4 (0.97) | TTRFABP4CCNA2CDK2MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1224240-B1 | 8-(ANILINO)-1-NAPHTHALENESULFONATE ANALOGS AND THEIR USE IN ANALYTE DETECTION ASSAYS | LIFESCAN INC (US) | 2005-02-23 | — | — | EP | claimed |
| EP-1510555-A1 | 8-(anilino)-1-naphthalenesulfonate analogs and their use in analyte detection assays | Lifescan, Inc. (US) | 2005-03-02 | — | — | EP | disclosed |
| EP-1224240-B1 | 8-(ANILINO)-1-NAPHTHALENESULFONATE ANALOGS AND THEIR USE IN ANALYTE DETECTION ASSAYS | LIFESCAN INC (US) | 2005-02-23 | — | — | EP | disclosed |
| CN-1413235-A | 8- (anilino) -1-naphthalenesulfonate analogs and their use in analyte detection assays | LIFESCAN INC (US) | 2003-04-23 | — | — | CN | disclosed |
| EP-1224240-A1 | 8-(ANILINO)-1-NAPHTHALENESULFONATE ANALOGS AND THEIR USE IN ANALYTE DETECTION ASSAYS | Lifescan, Inc. (US) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001030915-A1 | 8-(ANILINO)-1-NAPHTHALENESULFONATE ANALOGS AND THEIR USE IN ANALYTE DETECTION ASSAYS | LIFESCAN, INC. (US) | 2001-05-03 | — | — | WO | disclosed |
| US-6218571-B1 | COUPLING WITH 3-METHYL-2-BENZOTHIAZOLINONE HYDRAZONE HYDROCHLORIDE TO MAKE DYE; REDUCED DRIFT; GLUCOSE DETECTION IN BLOOD | LIFESCAN, INC. | 2001-04-17 | — | — | US | disclosed |