Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclopentanamine SCHEMBL6658971 | 0.82 | CYP1A2 (0.32) | MMP8MMP1ALDH1A1CYP1A2THRB | |
| Cyclohexylamine SCHEMBL6859288 | 0.81 | EPHX1 (0.34) | MMP8MMP1ALDH1A1EPHX1MMP2 | |
| Cyclohexylamine SCHEMBL20703173 | 0.78 | EPHX1 (0.38) | MMP8MMP1ALDH1A1EPHX1MMP2 | |
| Cyclohexane SCHEMBL17492352 | 0.78 | CYP2D6 (0.41) | CYP2D6 | |
| Cyclohexylamine SCHEMBL11686978 | 0.75 | SIGMAR1 (0.40) | SIGMAR1ALDH1A1EPHX1THRBMEN1 | |
| Cyclohexylamine SCHEMBL4447887 | 0.75 | SHBG (0.39) | MMP8MMP1ALDH1A1MMP2CYP1A2 | |
| Cyclooctanamine SCHEMBL6863778 | 0.74 | THRB (0.44) | MMP8MMP1ALDH1A1THRBMEN1 | |
| Cycloheptanamine SCHEMBL6866616 | 0.74 | THRB (0.44) | MMP8MMP1ALDH1A1THRBMEN1 | |
| Cyclohexylamine SCHEMBL8154944 | 0.74 | THRB (0.44) | MMP8MMP1ALDH1A1THRBMEN1 | |
| Cyclohexylamine SCHEMBL1679773 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005103015-A1 | TRIAZINE COMPOUNDS AND THEIR ANALOGS, COMPOSITIONS, AND METHODS | REDDY US THERAPEUTICS, INC. (US) | 2005-11-03 | — | — | WO | disclosed |
| EP-1560817-A1 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | Reddy US Therapeutics, Inc. (US) | 2005-08-10 | — | — | EP | disclosed |
| EP-1436266-A4 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | REDDY US THERAPEUTICS INC (US) | 2004-12-22 | — | — | EP | disclosed |
| WO-2004026844-A9 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | REDDY US THERAPEUTICS INC (US) | 2004-11-11 | — | — | WO | disclosed |
| EP-1436266-A2 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | Reddy US Therapeutics, Inc. (US) | 2004-07-14 | — | — | EP | disclosed |
| WO-2004026844-A1 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | REDDY US THERAPEUTICS, INC. (US) | 2004-04-01 | — | — | WO | disclosed |
| WO-2003024926-A2 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | REDDY US THERAPEUTICS, INC. (US) | 2003-03-27 | — | — | WO | disclosed |