Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 3/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6210484 | 0.87 | CTSL (0.39) | CTSK | |
| SCHEMBL6209760 | 0.86 | MT-CO2 (0.33) | DPP4MT-CO2ALOX5GRM4POLB | |
| SCHEMBL6209960 | 0.85 | CTSK (0.39) | DPP4DPP9CTSK | |
| SCHEMBL6209846 | 0.84 | DPP4 (0.35) | DPP4DPP8DPP7 | |
| SCHEMBL6209880 | 0.84 | PREP (0.35) | DPP4DPP8DPP9CTSK | |
| SCHEMBL4039452 | 0.81 | CTSK (0.32) | MT-CO2ALOX5GRM4CTSK | |
| SCHEMBL6211848 | 0.80 | NAMPT (0.32) | MT-CO2ALOX5GRM4 | |
| SCHEMBL4040192 | 0.80 | MT-CO2 (0.31) | MT-CO2ALOX5 | |
| SCHEMBL6208517 | 0.79 | HSD17B10 (0.41) | POLB | |
| SCHEMBL4043017 | 0.78 | CTSK (0.34) | DPP4DPP8DPP9CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | disclosed |