Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6209144 | 0.87 | SMYD3 (0.38) | TSHRSMYD3ALDH1A1 | |
| SCHEMBL6209880 | 0.87 | PREP (0.35) | GAAALDH1A1 | |
| SCHEMBL6208880 | 0.85 | KDM4E (0.42) | HSD17B10KDM4EHPGDTSHRSMYD3 | |
| SCHEMBL6208666 | 0.84 | KDM4E (0.39) | HSD17B10KDM4EHCRTR2HPGDTSHR | |
| SCHEMBL6210484 | 0.83 | CTSL (0.39) | ELOVL6 | |
| SCHEMBL6211558 | 0.83 | LMNA (0.38) | HSD17B10HCRTR2ELOVL6TSHRSMYD3 | |
| SCHEMBL4039220 | 0.82 | HSD17B10 (0.42) | HSD17B10KDM4EHCRTR2HPGDELOVL6 | |
| SCHEMBL6213622 | 0.82 | LMNA (0.38) | HSD17B10ELOVL6TSHRSMYD3POLB | |
| SCHEMBL6208825 | 0.81 | PAX8 (0.40) | KDM4EPOLBALDH1A1 | |
| SCHEMBL6212436 | 0.81 | LMNA (0.38) | HSD17B10HCRTR2ELOVL6TSHRSMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | claimed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | claimed |
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | disclosed |