Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.60 |
| ▸ | DRD3 | P35462 | 3/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 7/20 | 0.57 |
| ▸ | ADRA1B | P35368 | 7/20 | 0.57 |
| ▸ | ADRA1D | P25100 | 6/20 | 0.57 |
| ▸ | HTR1A | P08908 | 4/20 | 0.57 |
| ▸ | HTR7 | P34969 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | HTR6 | P50406 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6110726 | 0.91 | ADRA1A (0.56) | DRD2DRD3ADRA1AADRA1BADRA1D | |
| Hydrochloric Acid SCHEMBL6110922 | 0.90 | ADRA1A (0.55) | DRD2DRD3ADRA1AADRA1BADRA1D | |
| SCHEMBL4874588 | 0.88 | ADRA1A (0.56) | DRD2DRD3ADRA1AADRA1BADRA1D | |
| SCHEMBL6211200 | 0.88 | DRD2 (0.55) | DRD2DRD3ADRA1AADRA1BADRA1D | |
| SCHEMBL4527650 | 0.88 | HTR1A (0.56) | DRD2DRD3ADRA1AADRA1BADRA1D | |
| SCHEMBL6111886 | 0.88 | ADRA1A (0.55) | DRD2DRD3ADRA1AADRA1BADRA1D | |
| Hydrochloric Acid SCHEMBL4869554 | 0.88 | ADRA1A (0.55) | DRD2DRD3ADRA1AADRA1BADRA1D | |
| Hydrochloric Acid SCHEMBL6404518 | 0.87 | DRD2 (0.54) | DRD2DRD3ADRA1AADRA1BADRA1D | |
| SCHEMBL5812841 | 0.87 | ADRA1A (0.54) | DRD2DRD3ADRA1AADRA1BADRA1D | |
| Hydrochloric Acid SCHEMBL6111788 | 0.87 | ADRA1A (0.54) | DRD2DRD3ADRA1AADRA1BADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1495000-A4 | ALPHA, OMEGA-DICARBOXIMIDE DERIVATIVES AS USEFUL URO-SELECTIVE A1A ADRENOCEPTOR BLOCKERS | RANBAXY LAB LTD (IN) | 2005-10-05 | — | — | EP | claimed |
| EP-1495000-A1 | ALPHA, OMEGA-DICARBOXIMIDE DERIVATIVES AS USEFUL URO-SELECTIVE A1A ADRENOCEPTOR BLOCKERS | RANBAXY LABORATORIES, LTD. (IN) | 2005-01-12 | — | — | EP | claimed |
| WO-2003084928-A1 | ALPHA, OMEGA-DICARBOXIMIDE DERIVATIVES AS USEFUL URO-SELECTIVE Α1Α ADRENOCEPTOR BLOCKERS | RANBAXY LABORATORIES LIMITED (IN) | 2003-10-16 | — | — | WO | claimed |
| EP-1495000-A4 | ALPHA, OMEGA-DICARBOXIMIDE DERIVATIVES AS USEFUL URO-SELECTIVE A1A ADRENOCEPTOR BLOCKERS | RANBAXY LAB LTD (IN) | 2005-10-05 | — | — | EP | disclosed |
| EP-1495000-A1 | ALPHA, OMEGA-DICARBOXIMIDE DERIVATIVES AS USEFUL URO-SELECTIVE A1A ADRENOCEPTOR BLOCKERS | RANBAXY LABORATORIES, LTD. (IN) | 2005-01-12 | — | — | EP | disclosed |
| WO-2003084928-A1 | ALPHA, OMEGA-DICARBOXIMIDE DERIVATIVES AS USEFUL URO-SELECTIVE Α1Α ADRENOCEPTOR BLOCKERS | RANBAXY LABORATORIES LIMITED (IN) | 2003-10-16 | — | — | WO | disclosed |