Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 3/20 | 0.34 |
| ▸ | REN | P00797 | 9/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | MME | P08473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6211805 | 0.91 | CTSK (0.35) | CTSKKMT2A | |
| SCHEMBL6209026 | 0.90 | KDM4E (0.40) | CTSKMMP2MEN1KMT2A | |
| SCHEMBL6267150 | 0.86 | CTSK (0.33) | CTSK | |
| SCHEMBL4042797 | 0.83 | CTSK (0.45) | POLBCTSKRENCTSLCTSS | |
| SCHEMBL4043526 | 0.82 | KMT2A (0.35) | POLBCTSKRENMEN1KMT2A | |
| SCHEMBL4044663 | 0.81 | HSD17B10 (0.37) | RENKMT2A | |
| SCHEMBL4039943 | 0.81 | POLB (0.35) | POLBCTSKRENMMP2MMP8 | |
| SCHEMBL4043246 | 0.79 | POLB (0.36) | POLBCTSKRENMMP2MMP8 | |
| SCHEMBL4044024 | 0.79 | REN (0.38) | POLBCTSKRENKMT2ACTSL | |
| SCHEMBL4038283 | 0.78 | ALDH1A1 (0.38) | POLBCTSKRENMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | claimed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | claimed |