Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 4/20 | 0.31 |
| ▸ | CTSK | P43235 | 4/20 | 0.31 |
| ▸ | CTSS | P25774 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6211256 | 0.89 | RAB9A (0.31) | RAB9AHPGDTSHRHSD17B10LMNA | |
| SCHEMBL6211960 | 0.85 | CTSK (0.40) | RAB9ACTSLCTSKCTSSNPC1 | |
| SCHEMBL6587803 | 0.81 | RAB9A (0.40) | RAB9AHPGDTSHRHSD17B10LMNA | |
| SCHEMBL6210362 | 0.81 | CTSK (0.40) | CTSLCTSKCTSS | |
| SCHEMBL6600629 | 0.78 | HDAC3 (0.31) | CTSLCTSKCTSSGAA | |
| SCHEMBL6601255 | 0.76 | CTSL (0.30) | CTSLCTSKCTSS | |
| SCHEMBL6601774 | 0.76 | — | — | |
| SCHEMBL6673927 | 0.73 | CTSK (0.39) | RAB9ACTSLCTSKCTSSNPC1 | |
| SCHEMBL6213602 | 0.73 | CTSK (0.39) | RAB9ACTSLCTSKCTSSNPC1 | |
| SCHEMBL6843710 | 0.73 | CTSK (0.51) | CTSLCTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307203-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2005-08-17 | — | — | EP | claimed |
| EP-1307203-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-05-07 | — | — | EP | claimed |
| WO-2001070232-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-09-27 | — | — | WO | claimed |
| EP-1307203-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2005-08-17 | — | — | EP | disclosed |
| EP-1307203-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-05-07 | — | — | EP | disclosed |
| WO-2001070232-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-09-27 | — | — | WO | disclosed |