Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6092975 | 0.88 | LMNA (0.36) | LMNATP53PIN1HTTGAA | |
| SCHEMBL5333576 | 0.84 | MAPT (0.42) | LMNATP53EGFRPIN1HTT | |
| SCHEMBL4769141 | 0.83 | POLB (0.40) | LMNATP53PIN1HTTMEN1 | |
| SCHEMBL842636 | 0.82 | PIN1 (0.39) | LMNATP53EGFRPIN1HTT | |
| SCHEMBL4837631 | 0.82 | LMNA (0.38) | LMNATP53PIN1HTTMEN1 | |
| SCHEMBL4829956 | 0.81 | MAPT (0.41) | LMNATP53EGFRPIN1HTT | |
| SCHEMBL4773614 | 0.81 | MAPT (0.47) | LMNATP53PIN1HTTGAA | |
| SCHEMBL6096324 | 0.81 | BCHE (0.42) | LMNATP53 | |
| SCHEMBL4771390 | 0.81 | LMNA (0.37) | LMNATP53PIN1HTTMEN1 | |
| SCHEMBL4769051 | 0.81 | LMNA (0.37) | LMNATP53PIN1HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1511746-A2 | PROCESS FOR IMIDAZO[4,5-C]PYRIDIN-4-AMINES | 3M Innovative Properties Company (US) | 2005-03-09 | — | — | EP | disclosed |
| US-6743920-B2 | CHORINATION REPLACING HYDROXYL GROUPS OF 2,4-DIHYROXY-3-NITROPYRIDINE DERIVATIVE; AMINATION, HYDROXYARYLATION, REDUCTION AND CYCLIZATION; AMINE REPLACEMENT OF PHENOXY FUNCTIONALITY | 3M INNOVATIVE PROPERTIES COMPANY | 2004-06-01 | — | — | US | disclosed |
| US-20030232852-A1 | Process for imidazo[4,5-c]pyridin-4-amines | 3M INNOVATIVE PROPERTIES COMPANY | 2003-12-18 | — | — | US | disclosed |
| WO-2003101949-A2 | PROCESS FOR IMIDAZO[4,5-C]PYRIDIN-4-AMINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2003-12-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030232852-A1 | Process for imidazo[4,5-c]pyridin-4-amines | CPNE4, HTR4, IL4 | LMNA 2300/4885TP53 3168/4885PDCD1 693/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.