SCHEMBL621709

SCHEMBL621709

CC(C)C(NC(=O)COCCOCCOCC(=O)O)C(=O)NC(C=O)Cc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CTSB P07858 6/20 0.53
SMN1; SMN2 Q16637 1/20 0.44
CASP3 P42574 2/20 0.41
CASP1 P29466 1/20 0.41
CAPN1 P07384 2/20 0.41
CTSL P07711 1/20 0.41
CTSH P09668 1/20 0.41
CTSK P43235 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL622484 0.93 CTSB (0.52) CTSBSMN1; SMN2CAPN1
SCHEMBL10084537 0.92 CTSB (0.51) CTSBSMN1; SMN2CAPN1CTSLCTSH
SCHEMBL622475 0.88 CTSB (0.61) CTSBSMN1; SMN2CASP3CAPN1CTSL
SCHEMBL23234647 0.85 CTSB (0.58) CTSBSMN1; SMN2CAPN1CTSLCTSH
SCHEMBL622495 0.82 CTSB (0.58) CTSBSMN1; SMN2CASP1CAPN1CTSL
SCHEMBL20204722 0.80 CTSB (0.62) CTSBSMN1; SMN2CAPN1CTSLCTSH
SCHEMBL623362 0.80 CTSB (0.58) CTSBSMN1; SMN2CASP1CAPN1
SCHEMBL24588350 0.79 CTSB (0.49) CTSBCAPN1CTSL
SCHEMBL623797 0.79 CTSB (0.56) CTSBSMN1; SMN2CAPN1
SCHEMBL7361635 0.78 CTSB (0.59) CTSBSMN1; SMN2CAPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012021788-A2 DIPEPTIDE CALPAIN INHIBITORS BANYAN BIOMARKERS (US) 2012-02-16 WO disclosed