Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 6/20 | 0.34 |
| ▸ | ACHE | P22303 | 4/20 | 0.33 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4842188 | 0.81 | LTA4H (0.51) | LTA4HCHEK2ACHETBK1MEN1 | |
| SCHEMBL4838238 | 0.80 | ABCB1 (0.45) | ALDH1A1 | |
| SCHEMBL6218461 | 0.79 | TBK1 (0.44) | LTA4HCHEK2ACHETBK1MEN1 | |
| Trifluoroacetic Acid SCHEMBL4842767 | 0.77 | LTA4H (0.46) | LTA4HCHEK2ACHETBK1MEN1 | |
| Trifluoroacetic Acid SCHEMBL4845497 | 0.76 | ABCB1 (0.44) | ALDH1A1 | |
| SCHEMBL4844406 | 0.68 | ACHE (0.61) | LTA4HCHEK2ACHETBK1IKBKE | |
| SCHEMBL4839497 | 0.68 | NPSR1 (0.54) | ALDH1A1KMT2A | |
| SCHEMBL4840409 | 0.68 | ACHE (0.48) | LTA4HCHEK2ACHETBK1IKBKE | |
| SCHEMBL5259203 | 0.68 | TSHR (0.49) | ACHE | |
| SCHEMBL6218704 | 0.68 | ACHE (0.40) | LTA4HCHEK2ACHETBK1IKBKE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539759-A1 | USE OF AND SOME NOVEL IMIDAZOPYRIDINES | AstraZeneca AB (SE) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004016611-A1 | USE OF AND SOME NOVEL IMIDAZOPYRIDINES | ASTRAZENECA AB (SE) | 2004-02-26 | — | — | WO | disclosed |