Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CCR6 | P51684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL62190 | 0.71 | ALDH1A1 (0.40) | KMT2ATSHRALDH1A1GAALMNA | |
| SCHEMBL8495356 | 0.70 | CSF1R (0.36) | KMT2ATSHRJAK2JAK1SMN1; SMN2 | |
| SCHEMBL3038559 | 0.66 | CSF1R (0.39) | KMT2AALDH1A1GAALMNAHTT | |
| SCHEMBL9827990 | 0.65 | NPC1 (0.47) | TSHRALDH1A1GAAUSP2LMNA | |
| SCHEMBL9222308 | 0.64 | TSHR (0.51) | TSHRALDH1A1GAAUSP2LMNA | |
| SCHEMBL8045436 | 0.64 | BRD4 (0.36) | KMT2AALDH1A1JAK2JAK1HTT | |
| SCHEMBL15950879 | 0.63 | MAPT (0.51) | KMT2ATSHRALDH1A1USP2LMNA | |
| SCHEMBL2623135 | 0.63 | KDM4E (0.39) | KMT2ALMNAJAK2JAK1SMN1; SMN2 | |
| SCHEMBL8675770 | 0.62 | NPSR1 (0.42) | ALDH1A1LMNASMN1; SMN2HPGDHTT | |
| SCHEMBL1898390 | 0.62 | RAB9A (0.51) | KMT2ATSHRALDH1A1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1926703-B1 | NOVEL CARBOXYLIC ACID DERIVATIVES | DSM IP ASSETS BV (NL) | 2013-01-09 | — | — | EP | claimed |
| US-20090258887-A1 | Novel Carboxylic Acid Derivatives | DSM ASSETS B.V. (NL) | 2009-10-15 | — | — | US | claimed |
| EP-1926703-A1 | NOVEL CARBOXYLIC ACID DERIVATIVES | DSM IP Assets B.V. (NL) | 2008-06-04 | — | — | EP | claimed |
| WO-2007039059-A1 | NOVEL CARBOXYLIC ACID DERIVATIVES | DSM IP ASSETS B.V. (NL) | 2007-04-12 | — | — | WO | claimed |
| EP-1926703-B1 | NOVEL CARBOXYLIC ACID DERIVATIVES | DSM IP ASSETS BV (NL) | 2013-01-09 | — | — | EP | disclosed |
| US-8129562-B2 | Carboxylic acid derivatives | DSM IP ASSETS B.V. (NL) | 2012-03-06 | — | — | US | disclosed |
| US-20110124726-A1 | NOVEL CARBOXYLIC ACID DERIVATIVES | DSM IP ASSETS B.V. | 2011-05-26 | — | — | US | disclosed |
| US-7906496-B2 | Carboxylic acid derivatives | DSM IP ASSETS B.V. (NL) | 2011-03-15 | — | — | US | disclosed |
| US-20090258887-A1 | Novel Carboxylic Acid Derivatives | DSM ASSETS B.V. (NL) | 2009-10-15 | — | — | US | disclosed |
| EP-1926703-A1 | NOVEL CARBOXYLIC ACID DERIVATIVES | DSM IP Assets B.V. (NL) | 2008-06-04 | — | — | EP | disclosed |
| WO-2007039059-A1 | NOVEL CARBOXYLIC ACID DERIVATIVES | DSM IP ASSETS B.V. (NL) | 2007-04-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090258887-A1 | Novel Carboxylic Acid Derivatives | AADAC, ALDH7A1, DDC | KMT2A 1673/4885TSHR 2998/4885ALDH1A1 7/4885 |
| US-20110124726-A1 | NOVEL CARBOXYLIC ACID DERIVATIVES | AADAC, ALDH7A1, ALDH18A1 | KMT2A 1664/4885TSHR 2709/4885ALDH1A1 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.