Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | CLK2 | P49760 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6218398 | 0.85 | KCNH2 (0.49) | KCNH2POLBALDH1A1MAPTLMNA | |
| SCHEMBL7496082 | 0.84 | KCNH2 (0.48) | KCNH2POLBALDH1A1MAPTLMNA | |
| SCHEMBL116273 | 0.84 | ADRB2 (0.52) | KCNH2POLBALDH1A1ADRB2TDP1 | |
| SCHEMBL7122628 | 0.79 | KCNH2 (0.44) | KCNH2ALDH1A1MAPTLMNAADRB2 | |
| SCHEMBL28413965 | 0.78 | ADRB2 (0.55) | KCNH2POLBALDH1A1LMNAADRB2 | |
| SCHEMBL6215702 | 0.77 | TDP1 (0.48) | KCNH2MAPTLMNAADRB2TDP1 | |
| SCHEMBL1345260 | 0.77 | ADRB2 (0.44) | KCNH2POLBALDH1A1ADRB2GSK3B | |
| SCHEMBL1003852 | 0.77 | POLB (0.52) | KCNH2POLBALDH1A1MAPTLMNA | |
| SCHEMBL1989474 | 0.77 | ADRB2 (0.61) | KCNH2POLBALDH1A1LMNAADRB2 | |
| SCHEMBL29391687 | 0.77 | ADRB2 (0.61) | KCNH2POLBALDH1A1LMNAADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343766-B1 | CYCLIZATION PROCESS STEP IN THE MAKING OF QUINOLONES AND NAPHTHYRIDINES | PROCTER & GAMBLE (US) | 2005-07-27 | — | — | EP | disclosed |