Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRB | P23467 | 14/20 | 0.36 |
| ▸ | FDPS | P14324 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6222760 | 0.84 | FDPS (0.38) | FDPSMEN1KMT2ASLC6A3 | |
| SCHEMBL6222634 | 0.77 | FDPS (0.53) | FDPSMEN1KMT2A | |
| SCHEMBL2819185 | 0.74 | SLC6A3 (0.47) | PTPRBMEN1KMT2APTPN1SLC6A3 | |
| SCHEMBL4849187 | 0.72 | SLC6A3 (0.44) | FDPSMEN1KMT2ASLC6A3 | |
| SCHEMBL12468687 | 0.72 | KMT2A (0.44) | PTPRBMEN1KMT2APTPN1 | |
| SCHEMBL19603814 | 0.71 | PTPRB (0.35) | PTPRBPTPN1SLC6A3 | |
| SCHEMBL15319182 | 0.71 | PTPRB (0.43) | PTPRBPTPN1 | |
| SCHEMBL18793696 | 0.71 | SLC6A3 (0.36) | PTPRBPTPN1SLC6A3 | |
| SCHEMBL20738599 | 0.71 | SLC6A3 (0.36) | PTPRBPTPN1SLC6A3 | |
| SCHEMBL4848422 | 0.67 | PGK1 (0.44) | FDPSSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0854724-B1 | METHOD OF TREATING THE NAVICULAR DISEASE IN HORSES | NOVARTIS AG (CH) | 2005-03-16 | — | — | EP | claimed |
| US-6057306-A | ADMINISTERING BISPHOSPHONATES TO TREAT BONE DISEASE | NOVARTIS CORPORATION (US) | 2000-05-02 | — | — | US | claimed |
| EP-0854724-A1 | METHOD OF TREATING THE NAVICULAR DISEASE IN HORSES | Novartis AG (CH) | 1998-07-29 | — | — | EP | claimed |
| WO-1997012619-A1 | METHOD OF TREATING THE NAVICULAR DISEASE IN HORSES | NOVARTIS AG (CH) | 1997-04-10 | — | — | WO | claimed |
| EP-0854724-B1 | METHOD OF TREATING THE NAVICULAR DISEASE IN HORSES | NOVARTIS AG (CH) | 2005-03-16 | — | — | EP | disclosed |
| US-6057306-A | ADMINISTERING BISPHOSPHONATES TO TREAT BONE DISEASE | NOVARTIS CORPORATION (US) | 2000-05-02 | — | — | US | disclosed |
| EP-0854724-A1 | METHOD OF TREATING THE NAVICULAR DISEASE IN HORSES | Novartis AG (CH) | 1998-07-29 | — | — | EP | disclosed |
| WO-1997012619-A1 | METHOD OF TREATING THE NAVICULAR DISEASE IN HORSES | NOVARTIS AG (CH) | 1997-04-10 | — | — | WO | disclosed |