SCHEMBL622326

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL623270	0.89	CYP1A2 (0.48)	TACR3CYP1A2CYP3A4CYP2D6CYP2C9
	SCHEMBL624193	0.81	TACR3 (0.42)	TACR3CYP1A2CYP3A4CYP2D6CYP2C9
	SCHEMBL624155	0.78	DRD2 (0.51)	KDM4EALDH1A1GAANPSR1LRRK2
	SCHEMBL623132	0.77	PTGDR2 (0.42)	KDM4EALDH1A1LMNAGAAHPGD
	SCHEMBL623692	0.72	HRH4 (0.47)	HRH4KDM4EALDH1A1LMNAHPGD
	SCHEMBL624600	0.72	DRD2 (0.41)	LRRK2ACACB
	SCHEMBL624199	0.72	CYP1A2 (0.48)	TACR3CYP1A2CYP3A4CYP2D6CYP2C9
	SCHEMBL623290	0.72	PSMB8 (0.40)	TACR3CYP1A2CYP3A4CYP2D6CYP2C9
	SCHEMBL623163	0.72	ALDH1A1 (0.41)	TACR3KDM4EALDH1A1LMNAGAA
	SCHEMBL624511	0.70	GPR119 (0.52)	ALDH1A1LMNAHTTLRRK2ACACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.