Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 9/20 | 0.40 |
| ▸ | ELANE | P08246 | 4/20 | 0.38 |
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6223291 | 0.89 | HTR3A (0.39) | HTR3AELANECNR2CNR1 | |
| SCHEMBL3534667 | 0.81 | HTR3A (0.47) | HTR3AELANECNR2CNR1 | |
| SCHEMBL6223554 | 0.81 | PDE4A (0.47) | ELANE | |
| SCHEMBL6223244 | 0.80 | EPHX1 (0.40) | CNR1 | |
| SCHEMBL3533287 | 0.77 | KDM4E (0.45) | HTR3AELANECNR2CNR1 | |
| Hydrochloric Acid SCHEMBL3534671 | 0.76 | HTR3A (0.44) | HTR3AELANECNR2CNR1 | |
| SCHEMBL27521014 | 0.74 | ELANE (0.41) | HTR3AELANECNR2CNR1 | |
| SCHEMBL9262806 | 0.69 | PRKCB (0.44) | HTR3AELANECNR2CNR1 | |
| SCHEMBL5552779 | 0.69 | PDE4A (0.55) | HTR3AELANECNR2CNR1 | |
| SCHEMBL3540199 | 0.69 | CNR1 (0.53) | HTR3AELANECNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1330455-B1 | NOVEL 7-AZAINDOLES, USE THEREOF AS PHOSPHODIESTERASE 4 INHIBITORS AND METHOD FOR PRODUCING THE SAME | ELBION AG (DE) | 2005-08-03 | — | — | EP | disclosed |
| EP-1330455-A1 | NOVEL 7-AZAINDOLES, USE THEREOF AS PHOSPHODIESTERASE 4 INHIBITORS AND METHOD FOR PRODUCING THE SAME | Elbion AG (DE) | 2003-07-30 | — | — | EP | disclosed |
| WO-2002034747-A1 | NOVEL 7-AZAINDOLES, USE THEREOF AS PHOSPHODIESTERASE 4 INHIBITORS AND METHOD FOR PRODUCING THE SAME | ELBION AG (DE) | 2002-05-02 | — | — | WO | disclosed |